ENSMUSG00000030688


Mus musculus

Features
Gene ID: ENSMUSG00000030688
  
Biological name :Stard10
  
Synonyms : Q9JMD3 / Stard10 / START domain containing 10
  
Possible biological names infered from orthology : Q9Y365 / StAR related lipid transfer domain containing 10
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E2
Gene start: 101317086
Gene end: 101346626
  
Corresponding Affymetrix probe sets: 10555460 (MoGene1.0st)   1448956_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148114
Ensembl peptide - ENSMUSP00000134156
Ensembl peptide - ENSMUSP00000134430
Ensembl peptide - ENSMUSP00000032927
Ensembl peptide - ENSMUSP00000127962
Ensembl peptide - ENSMUSP00000129408
Ensembl peptide - ENSMUSP00000133002
Ensembl peptide - ENSMUSP00000133955
Ensembl peptide - ENSMUSP00000133985
Ensembl peptide - ENSMUSP00000134138
NCBI entrez gene - 56018     See in Manteia.
MGI - MGI:1860093
RefSeq - XM_011241865
RefSeq - NM_019990
RefSeq Peptide - NP_064374
swissprot - G3UYM0
swissprot - G3UYN6
swissprot - G3UZB9
swissprot - G3UW37
swissprot - E9PVP0
swissprot - Q0VG22
swissprot - Q9JMD3
swissprot - G3UY87
swissprot - G3UY59
Ensembl - ENSMUSG00000030688
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stard10ENSDARG00000097718Danio rerio
 ENSGALG00000028681Gallus gallus
 Q9Y365ENSG00000214530Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002913  START domain
 IPR023393  START-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0032782 bile acid secretion IMP
 biological_processGO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0046581 intercellular canaliculus IDA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000558 abnormal tibia morphology "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002310 resistance to fatty liver development "less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0004772 abnormal bile secretion "any anomaly in the quantity or rate of bile secreted through the bile ducts in a given length of time" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0004773 abnormal bile composition "any alteration in the chemical make up of the greenish-yellow fluid secreted by the liver; normally contains bile acids and salts such as sodium glycocholate and sodium taurocholate as well as cholesterol, biliverdin and bilirubin, mucus, fat, lecithin, and cells and cellular debris" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0004777 abnormal phospholipid level "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0004789 increased bile salt level "increased concentration of the steroid salts derived from cholesterol in the liver, produced as bile acids and secreted in the biliary sytem as bile salts; these play an important role in the digestion and absorption of fats" [MESH:D04.808.105, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0005365 abnormal bile salt homeostasis "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86154]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd-Spns2tm1b(KOMP)Wtsi/WtsiH

 MP:0009356 decreased liver triglyceride level "lower than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0010026 decreased liver cholesterol level "less than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf2tm1.1Jw Nxf3tm1.1Jw/Y,Tg(Ddx4-cre)1Dcas/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021608 Lpcat1 / Q3TFD2 / Lysophosphatidylcholine acyltransferase 1 / Q8NF37*  / complex / reaction
 ENSMUSG00000024387 Csnk2b / P67871 / Casein kinase II subunit beta / P67870* / casein kinase 2 beta*  / reaction
 ENSMUSG00000046707 O54833 / Csnk2a2 / Casein kinase II subunit alpha / P19784* / casein kinase 2 alpha 2*  / reaction
 ENSMUSG00000101523 Q60737 / Gm10031 / predicted pseudogene 10031 / Q8NEV1* / P68400* / CSNK2A1* / CSNK2A3* / casein kinase 2 alpha 1* / casein kinase 2 alpha 3*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr