MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
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MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
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MP:0000382 | underdeveloped hair follicles | "arrest of or retarded differentiation of the epidermal invaginations from which the hair shaft develops" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
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Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
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MP:0000416 | sparse fur | "fur that is significantly less dense" [J:46854] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0000417 | short hair | "reduced average length of the hairs" [J:64948] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Prss8fr/Prss8+,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
Allelic Composition: Prss8fr/Prss8fr,Spint2Gt(KST272)Byg/Spint2Gt(KST272)Byg Genetic Background: involves: 129P2/OlaHsd * DBA
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MP:0001190 | reddish skin | "skin has a more intense ruddy appearance than normal, often due to capillary congestion" [J:65038] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001240 | abnormal cornified layer morphology | "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
Allelic Composition: Prss8Gt(IST10122F12)Tigm/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001274 | curly vibrissae | "whiskers twisted into coils or spirals" [J:47620] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001278 | kinked vibrissae | "sharp bends in the vibrissae" [J:56641] |
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Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001282 | short vibrissae | "decreased length of the vibrissae" [J:30249] |
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Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001284 | absent vibrissae | "missing whiskers" [J:18378] |
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Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8Gt(IST10122F12)Tigm/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
Allelic Composition: Prss8fr/Prss8fr,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
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MP:0001511 | disheveled coat | "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0001547 | abnormal lipid level | "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0001711 | abnormal placenta | |
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Allelic Composition: Prss8fr/Prss8fr,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
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MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0002098 | abnormal vibrissae morphology | "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tgfbr2tm1.1Hlm/Tgfbr2tm1.1Hlm Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0002796 | impaired skin barrier function | "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Prss8Gt(IST10122F12)Tigm/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
Allelic Composition: Prss8tm1.1Bug/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0002908 | delayed wound healing | "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037] |
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Allelic Composition: Prss8tm1.1Bug/Prss8tm1.1Bug Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0003051 | curly tail | "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Prss8fr/Prss8+,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
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MP:0003054 | spina bifida | "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Prss8fr/Prss8+,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
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MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0003812 | abnormal hair medulla | "anomalies of hair medullary cell formation and arrangement of the innermost core of the hair shaft " [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0003853 | dry skin | "skin characterized by the lack of natural or normal moisture" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Prss8fr/Prss8tm1.1Hum Genetic Background: involves: 129/Sv * FS/EiJ
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Prss8tm1.1Bug/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0009675 | orthokeratosis | "thickening of the stratum corneum of the epidermis (hyperkeratosis) with non-nucleated keratinocytes retained in this layer" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0010179 | rough coat | "coat does not have the usual smooth appearance" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Actbtm1Npa/Actbtm1Npa Genetic Background: involves: BALB/cJ
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Prss8tm1.1Bug/Prss8Gt(IST10122F12)Tigm Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * C57BL/6N
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MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Prss8fr/Prss8+,Spint2Gt(KST272)Byg/Spint2Gt(KST272)Byg Genetic Background: involves: 129P2/OlaHsd * DBA
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Prss8fr/Prss8+,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Prss8fr/Prss8fr,Spint1tm1Bug/Spint1tm1Bug Genetic Background: involves: 129S6/SvEvTac * DBA
Allelic Composition: Prss8fr/Prss8fr,Spint2Gt(KST272)Byg/Spint2Gt(KST272)Byg Genetic Background: involves: 129P2/OlaHsd * DBA
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MP:0013589 | thymus medulla hypoplasia | "underdevelopment or reduced size, usually due to a reduced cell number, of the inner area of thymus lobules" [MGI:Anna] |
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Allelic Composition: Wt1tm1Nhsn/Wt1+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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