ENSMUSG00000031201


Mus musculus

Features
Gene ID: ENSMUSG00000031201
  
Biological name :Brcc3
  
Synonyms : Brcc3 / Lys-63-specific deubiquitinase BRCC36 / P46737
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A7.3
Gene start: 75416628
Gene end: 75454001
  
Corresponding Affymetrix probe sets: 10600512 (MoGene1.0st)   1426605_at (Mouse Genome 430 2.0 Array)   1437553_at (Mouse Genome 430 2.0 Array)   1447778_x_at (Mouse Genome 430 2.0 Array)   1452128_a_at (Mouse Genome 430 2.0 Array)   1456141_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033544
Ensembl peptide - ENSMUSP00000114057
Ensembl peptide - ENSMUSP00000123031
Ensembl peptide - ENSMUSP00000127772
Ensembl peptide - ENSMUSP00000109708
NCBI entrez gene - 210766     See in Manteia.
MGI - MGI:2389572
RefSeq - XM_011247554
RefSeq - NM_001166457
RefSeq - NM_001166459
RefSeq - NM_145956
RefSeq Peptide - NP_001159929
RefSeq Peptide - NP_666068
RefSeq Peptide - NP_001159931
RefSeq Peptide - NP_001345665
RefSeq Peptide - NP_001345666
swissprot - P46737
swissprot - E9Q0P6
swissprot - A3KGA8
Ensembl - ENSMUSG00000031201
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brcc3ENSDARG00000098242Danio rerio
 BRCC3ENSGALG00000005383Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm5136 / Q7M757 / predicted gene 5136 / BRCC3* / P46736* / BRCA1/BRCA2-containing complex subunit 3*ENSMUSG0000011203985


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR033860  Brcc36 isopeptidase
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair ISS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010165 response to X-ray ISO
 biological_processGO:0010212 response to ionizing radiation ISO
 biological_processGO:0045739 positive regulation of DNA repair ISO
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 biological_processGO:0070537 histone H2A K63-linked deubiquitination ISO
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint ISO
 cellular_componentGO:0000151 ubiquitin ligase complex ISO
 cellular_componentGO:0000152 nuclear ubiquitin ligase complex ISO
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0070531 BRCA1-A complex IEA
 cellular_componentGO:0070552 BRISC complex IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030234 enzyme regulator activity ISO
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding ISS
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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