ENSDARG00000098242


Danio rerio

Features
Gene ID: ENSDARG00000098242
  
Biological name :brcc3
  
Synonyms : BRCA1/BRCA2-containing complex, subunit 3 / brcc3
  
Possible biological names infered from orthology : Gm5136 / Lys-63-specific deubiquitinase BRCC36 / P46736 / P46737 / predicted gene 5136 / Q7M757
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 44547450
Gene end: 44556411
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130611
Ensembl peptide - ENSDARP00000133727
swissprot - A0A0R4ICH2
swissprot - A0A0R4IER2
ZFIN ID - ZDB-GENE-100215-1
Ensembl - ENSDARG00000098242
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BRCC3ENSGALG00000005383Gallus gallus
 BRCC3ENSG00000185515Homo sapiens
 Brcc3ENSMUSG00000031201Mus musculus
 Gm5136ENSMUSG00000112039Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR033860  Brcc36 isopeptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 cellular_componentGO:0070531 BRCA1-A complex IEA
 cellular_componentGO:0070552 BRISC complex IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel absent , abnormal
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 ZFA:0005559 vascular sprouts vascular sprouts increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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