ENSMUSG00000031785


Mus musculus

Features
Gene ID: ENSMUSG00000031785
  
Biological name :Adgrg1
  
Synonyms : Adgrg1 / Adhesion G-protein coupled receptor G1 ADGRG1 N-terminal fragment ADGRG1 C-terminal fragment / Q8K209
  
Possible biological names infered from orthology : adhesion G protein-coupled receptor G1 / Q9Y653
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C5
Gene start: 94974751
Gene end: 95014217
  
Corresponding Affymetrix probe sets: 10574259 (MoGene1.0st)   1421118_a_at (Mouse Genome 430 2.0 Array)   1433485_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148309
Ensembl peptide - ENSMUSP00000148304
Ensembl peptide - ENSMUSP00000148331
Ensembl peptide - ENSMUSP00000148742
Ensembl peptide - ENSMUSP00000148650
Ensembl peptide - ENSMUSP00000148644
Ensembl peptide - ENSMUSP00000148439
Ensembl peptide - ENSMUSP00000148412
Ensembl peptide - ENSMUSP00000148386
Ensembl peptide - ENSMUSP00000148374
Ensembl peptide - ENSMUSP00000148349
Ensembl peptide - ENSMUSP00000090959
Ensembl peptide - ENSMUSP00000137520
NCBI entrez gene - 14766     See in Manteia.
MGI - MGI:1340051
RefSeq - XM_017312577
RefSeq - XM_006530685
RefSeq - XM_006530686
RefSeq - XM_006530687
RefSeq - XM_006530688
RefSeq - XM_006530689
RefSeq - XM_006530690
RefSeq - XM_006530691
RefSeq - XM_006530692
RefSeq - XM_006530693
RefSeq - XM_006530694
RefSeq - XM_006530695
RefSeq - XM_006530696
RefSeq - XM_006530697
RefSeq - NM_001198894
RefSeq - NM_018882
RefSeq - XM_006530680
RefSeq - XM_006530681
RefSeq - XM_006530683
RefSeq Peptide - NP_001185823
RefSeq Peptide - NP_061370
swissprot - A0A1D5RLN4
swissprot - A0A1D5RLK9
swissprot - A0A1D5RLI8
swissprot - A0A1D5RLH8
swissprot - A0A1D5RME3
swissprot - A0A1D5RLE2
swissprot - A0A1D5RLC4
swissprot - Q8K209
swissprot - A0A1D5RLB9
swissprot - A0A1D5RLF7
swissprot - A0A1D5RM68
Ensembl - ENSMUSG00000031785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADGRG1ENSGALG00000037939Gallus gallus
 ADGRG1ENSG00000205336Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adgrg5 / Q3V3Z3 / Adhesion G-protein coupled receptor G5 / Q8IZF4*ENSMUSG0000006157727
Adgrg6 / Q6F3F9 / Adhesion G-protein coupled receptor G6 ADGRG6 N-terminal fragment ADGRG6 C-terminal fragment / Q86SQ4* / adhesion G protein-coupled receptor G6*ENSMUSG0000003911625
Adgrg3 / Q8R0T6 / Adhesion G protein-coupled receptor G3 / Q86Y34*ENSMUSG0000006047024
Adgrg2 / Q8CJ12 / Adhesion G-protein coupled receptor G2 / Q8IZP9*ENSMUSG0000003129823
Adgrg7 / Q8BM96 / Adhesion G-protein coupled receptor G7 / Q96K78*ENSMUSG0000002275516
Adgrg4 / B7ZCC9 / Adhesion G-protein coupled receptor G4 / Q8IZF6*ENSMUSG000000538524


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR003910  GPCR, family 2, orphan receptor, GPR1/GPR3/GPR5
 IPR017981  GPCR, family 2-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis ISO
 biological_processGO:0007155 cell adhesion ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007266 Rho protein signal transduction ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0010573 vascular endothelial growth factor production ISS
 biological_processGO:0016477 cell migration ISS
 biological_processGO:0021796 cerebral cortex regionalization IMP
 biological_processGO:0021801 cerebral cortex radial glia guided migration IMP
 biological_processGO:0021819 layer formation in cerebral cortex IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IMP
 biological_processGO:0045785 positive regulation of cell adhesion ISS
 biological_processGO:0070528 protein kinase C signaling ISS
 biological_processGO:0072520 seminiferous tubule development IMP
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IMP
 biological_processGO:2001223 negative regulation of neuron migration IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097451 glial limiting end-foot IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IMP
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Spi1tm1Rpd/Spi1tm1Rpd
Genetic Background: involves: 129/Sv

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adamts1tm1Dgen/Adamts1tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003648 abnormal radial glial cell morphology "anomalous structure, number, or composition of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Spi1tm1Rpd/Spi1tm1Rpd
Genetic Background: involves: 129/Sv

 MP:0003998 decreased thermal nociceptive threshold "a lower than average point at which thermal pain sensation is first detectable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adamts1tm1Dgen/Adamts1tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0004097 abnormal cerebellar cortex morphology "any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Adamts1tm1Dgen/Adamts1tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Spi1tm1Rpd/Spi1tm1Rpd
Genetic Background: involves: 129/Sv

 MP:0008030 abnormal Cajal-Retzius cell morphology "any abnormality of the distinct population of large, bipolar cells, distributed in a continuous band along the marginal zone of the cortex extending to the molecular layer of the dentate gyrus" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spi1tm1Rpd/Spi1tm1Rpd
Genetic Background: involves: 129/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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