ENSMUSG00000031298


Mus musculus

Features
Gene ID: ENSMUSG00000031298
  
Biological name :Adgrg2
  
Synonyms : Adgrg2 / Adhesion G-protein coupled receptor G2 / Q8CJ12
  
Possible biological names infered from orthology : Q8IZP9
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F4
Gene start: 160390690
Gene end: 160498070
  
Corresponding Affymetrix probe sets: 10602896 (MoGene1.0st)   1438350_at (Mouse Genome 430 2.0 Array)   1439795_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108027
Ensembl peptide - ENSMUSP00000108024
Ensembl peptide - ENSMUSP00000118598
Ensembl peptide - ENSMUSP00000108017
Ensembl peptide - ENSMUSP00000108019
Ensembl peptide - ENSMUSP00000108020
Ensembl peptide - ENSMUSP00000108021
Ensembl peptide - ENSMUSP00000108023
NCBI entrez gene - 237175     See in Manteia.
MGI - MGI:2446854
RefSeq - XM_017318479
RefSeq - XM_006528810
RefSeq - XM_006528811
RefSeq - XM_006528812
RefSeq - XM_006528813
RefSeq - XM_006528814
RefSeq - XM_006528816
RefSeq - XM_006528819
RefSeq - XM_006528824
RefSeq - XM_006528827
RefSeq - XM_006528829
RefSeq - XM_011247817
RefSeq - NM_001079847
RefSeq - NM_001079848
RefSeq - NM_001079857
RefSeq - NM_001290445
RefSeq - NM_001290446
RefSeq - NM_178712
RefSeq - XM_006528806
RefSeq - XM_006528807
RefSeq - XM_006528808
RefSeq - XM_006528809
RefSeq Peptide - NP_848827
RefSeq Peptide - NP_001073316
RefSeq Peptide - NP_001073317
RefSeq Peptide - NP_001073326
RefSeq Peptide - NP_001277374
RefSeq Peptide - NP_001277375
swissprot - Q8CJ12
swissprot - Q14AX7
swissprot - Q14BH6
swissprot - A2AHQ2
swissprot - A2AHP7
Ensembl - ENSMUSG00000031298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrg2aENSDARG00000088137Danio rerio
 si:dkey-259j3.5ENSDARG00000088937Danio rerio
 ADGRG2ENSGALG00000016511Gallus gallus
 ADGRG2ENSG00000173698Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adgrg6 / Q6F3F9 / Adhesion G-protein coupled receptor G6 ADGRG6 N-terminal fragment ADGRG6 C-terminal fragment / Q86SQ4* / adhesion G protein-coupled receptor G6*ENSMUSG0000003911632
Adgrg1 / Q8K209 / Adhesion G-protein coupled receptor G1 ADGRG1 N-terminal fragment ADGRG1 C-terminal fragment / Q9Y653* / adhesion G protein-coupled receptor G1*ENSMUSG0000003178516
Adgrg5 / Q3V3Z3 / Adhesion G-protein coupled receptor G5 / Q8IZF4*ENSMUSG0000006157716
Adgrg3 / Q8R0T6 / Adhesion G protein-coupled receptor G3 / Q86Y34*ENSMUSG0000006047015
Adgrg7 / Q8BM96 / Adhesion G-protein coupled receptor G7 / Q96K78*ENSMUSG0000002275513
Adgrg4 / B7ZCC9 / Adhesion G-protein coupled receptor G4 / Q8IZF6*ENSMUSG000000538527


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001148 enlarged testes "increased size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0001784 abnormal fluid regulation "anomalous control of intracellular and/or extracellular fluid " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0002662 abnormal cauda "anomalous structure of the tail of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0004930 small epididymis "decrease in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0009140 dilated efferent ductules of testis "an expansion in the volume or area of the lumen of the small seminal ducts that lead from the testis to the head of the epididymis, usually with an increase in contained fluid" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0009234 absent sperm head "absence of the head segment of the sperm cell" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0009237 kinked sperm flagellum "a sharp bend or zigzag in the sperm tail" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0009257 dilated seminiferous tubules "the luminal space of the seminiferous tubules is increased in volume or area, usually with an increase in contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac5tm1Eno/Hdac5tm1Eno,Hdac9tm1Eno/Hdac9tm1Eno
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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