ENSMUSG00000032026


Mus musculus

Features
Gene ID: ENSMUSG00000032026
  
Biological name :Rexo2
  
Synonyms : Mus musculus RNA exonuclease 2 (Rexo2), transcript variant 3, mRNA. / Q9D8S4 / Rexo2
  
Possible biological names infered from orthology : Q9Y3B8 / RNA exonuclease 2
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.3
Gene start: 48468512
Gene end: 48480623
  
Corresponding Affymetrix probe sets: 10593205 (MoGene1.0st)   1451259_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034524
Ensembl peptide - ENSMUSP00000149784
Ensembl peptide - ENSMUSP00000149774
Ensembl peptide - ENSMUSP00000149074
NCBI entrez gene - 104444     See in Manteia.
MGI - MGI:1888981
RefSeq - XM_006509934
RefSeq - NM_001357503
RefSeq - NM_024233
RefSeq Peptide - NP_001344432
RefSeq Peptide - NP_077195
swissprot - Q9D8S4
swissprot - A0A1L1SS70
swissprot - A0A1L1SQJ5
swissprot - A0A1L1SS58
Ensembl - ENSMUSG00000032026
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smfnENSDARG00000009806Danio rerio
 REXO2ENSGALG00000035980Gallus gallus
 REXO2ENSG00000076043Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR022894  Oligoribonuclease
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IBA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005925 focal adhesion IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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