ENSMUSG00000032127


Mus musculus

Features
Gene ID: ENSMUSG00000032127
  
Biological name :Vps11
  
Synonyms : Q91W86 / Vps11 / VPS11, CORVET/HOPS core subunit
  
Possible biological names infered from orthology : Q9H270
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.2
Gene start: 44347749
Gene end: 44361670
  
Corresponding Affymetrix probe sets: 10592830 (MoGene1.0st)   1428109_at (Mouse Genome 430 2.0 Array)   1428110_x_at (Mouse Genome 430 2.0 Array)   1441922_x_at (Mouse Genome 430 2.0 Array)   1452489_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034644
Ensembl peptide - ENSMUSP00000150989
Ensembl peptide - ENSMUSP00000150333
Ensembl peptide - ENSMUSP00000149457
Ensembl peptide - ENSMUSP00000148911
NCBI entrez gene - 71732     See in Manteia.
MGI - MGI:1918982
RefSeq - XM_017313599
RefSeq - NM_027889
RefSeq - XM_017313598
RefSeq Peptide - NP_082165
swissprot - A0A1L1STI8
swissprot - A0A1L1SV27
swissprot - Q91W86
swissprot - A0A1L1SRH3
swissprot - A0A1L1SQ62
Ensembl - ENSMUSG00000032127
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps11ENSDARG00000036338Danio rerio
 VPS11ENSGALG00000029536Gallus gallus
 VPS11ENSG00000160695Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR001841  Zinc finger, RING-type
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016024  Armadillo-type fold
 IPR016528  Vacuolar protein sorting-associated protein 11
 IPR024763  Vacuolar protein sorting protein 11, C-terminal
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007032 endosome organization IBA
 biological_processGO:0007040 lysosome organization IBA
 biological_processGO:0008333 endosome to lysosome transport ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0031647 regulation of protein stability ISO
 biological_processGO:0034058 endosomal vesicle fusion ISO
 biological_processGO:0035542 regulation of SNARE complex assembly IBA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1902115 regulation of organelle assembly ISO
 biological_processGO:1903364 positive regulation of cellular protein catabolic process ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 biological_processGO:2000643 positive regulation of early endosome to late endosome transport ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IDA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030139 endocytic vesicle ISS
 cellular_componentGO:0030897 HOPS complex ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0033263 CORVET complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0019905 syntaxin binding ISO
 molecular_functionGO:0030674 protein binding, bridging IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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