ENSMUSG00000032204


Mus musculus

Features
Gene ID: ENSMUSG00000032204
  
Biological name :Aqp9
  
Synonyms : Aqp9 / Aquaporin-9 / Q9JJJ3
  
Possible biological names infered from orthology : O43315
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: D
Gene start: 71110659
Gene end: 71168682
  
Corresponding Affymetrix probe sets: 10594825 (MoGene1.0st)   1421605_a_at (Mouse Genome 430 2.0 Array)   1424011_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116785
Ensembl peptide - ENSMUSP00000050127
Ensembl peptide - ENSMUSP00000074063
Ensembl peptide - ENSMUSP00000109200
NCBI entrez gene - 64008     See in Manteia.
MGI - MGI:1891066
RefSeq - XM_011242783
RefSeq - NM_001271843
RefSeq - NM_022026
RefSeq - XM_006511331
RefSeq - XM_006511332
RefSeq - XM_011242782
RefSeq Peptide - NP_001258772
RefSeq Peptide - NP_071309
swissprot - Q4FK77
swissprot - E9Q8P3
swissprot - Q9JJJ3
swissprot - D3YYD6
Ensembl - ENSMUSG00000032204
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aqp9bENSDARG00000053480Danio rerio
 AQP9ENSGALG00000004261Gallus gallus
 AQP9ENSG00000103569Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Aqp3 / Q8R2N1 / Aquaporin-3 / Q92482* / aquaporin 3 (Gill blood group)*ENSMUSG0000002843540
Aqp7 / O54794 / Aquaporin-7 / O14520* / AL845331.2*ENSMUSG0000002842736


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR015685  Aquaporin 9
 IPR022357  Major intrinsic protein, conserved site
 IPR023271  Aquaporin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006833 water transport IEA
 biological_processGO:0006863 purine nucleobase transport IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0015791 polyol transport IEA
 biological_processGO:0015793 glycerol transport IEA
 biological_processGO:0015837 amine transport IEA
 biological_processGO:0015855 pyrimidine nucleobase transport IEA
 biological_processGO:0046689 response to mercury ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071918 urea transmembrane transport IEA
 biological_processGO:0072531 pyrimidine-containing compound transmembrane transport IEA
 biological_processGO:1904823 purine nucleobase transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0046930 pore complex IEA
 molecular_functionGO:0005345 purine nucleobase transmembrane transporter activity IEA
 molecular_functionGO:0005350 pyrimidine nucleobase transmembrane transporter activity IEA
 molecular_functionGO:0015250 water channel activity IEA
 molecular_functionGO:0015254 glycerol channel activity ISO
 molecular_functionGO:0015265 urea channel activity ISO
 molecular_functionGO:0015267 channel activity IEA
 molecular_functionGO:0015288 porin activity IEA


Pathways (from Reactome)
Pathway description
Transport of glycerol from adipocytes to the liver by Aquaporins
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Fastm1Ach/Fastm1Ach,Tg(GZMB-cre)1Jcb/?
Genetic Background: involves: C57BL/6 * FVB/N

 MP:0003443 increased circulating glycerol level "higher than normal concentration of glycerol in the blood" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Fastm1Ach/Fastm1Ach,Tg(GZMB-cre)1Jcb/?
Genetic Background: involves: C57BL/6 * FVB/N

Allelic Composition: Aqp9tm1Nlsn/Aqp9tm1Nlsn,Leprdb/Leprdb
Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BLKS/J

 MP:0003656 abnormal erythrocyte physiology "functional anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Aqp9tm1Nlsn/Aqp9tm1Nlsn,Leprdb/Leprdb
Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BLKS/J

 MP:0003657 abnormal erythrocyte lysis "increase or decrease in the ability of RBCs to withstand changes in osmolarity" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Aqp9tm1Nlsn/Aqp9tm1Nlsn,Leprdb/Leprdb
Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BLKS/J

 MP:0005026 decreased susceptibility to parasitic infection "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Aqp9tm1Nlsn/Aqp9tm1Nlsn,Leprdb/Leprdb
Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BLKS/J

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Aqp9tm1Nlsn/Aqp9tm1Nlsn,Leprdb/Leprdb
Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BLKS/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032204 Aqp9 / Q9JJJ3 / Aquaporin-9 / O43315*  / complex






 

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