ENSMUSG00000032410


Mus musculus

Features
Gene ID: ENSMUSG00000032410
  
Biological name :Xrn1
  
Synonyms : 5-3 exoribonuclease 1 / Xrn1
  
Possible biological names infered from orthology : Q8IZH2
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 95954760
Gene end: 96057803
  
Corresponding Affymetrix probe sets: 10587942 (MoGene1.0st)   1437475_at (Mouse Genome 430 2.0 Array)   1442141_at (Mouse Genome 430 2.0 Array)   1450308_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139510
Ensembl peptide - ENSMUSP00000140278
Ensembl peptide - ENSMUSP00000140004
Ensembl peptide - ENSMUSP00000034981
NCBI entrez gene - 24127     See in Manteia.
MGI - MGI:891964
RefSeq - XM_006511154
RefSeq - XM_011242743
RefSeq - XM_006511156
RefSeq - XM_006511155
RefSeq - NM_001311130
RefSeq - NM_011916
RefSeq Peptide - NP_001298059
RefSeq Peptide - NP_036046
swissprot - A0A087WQN7
swissprot - A0A087WNV6
swissprot - F8VQ87
swissprot - A0A087WQ18
Ensembl - ENSMUSG00000032410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xrn1ENSDARG00000091652Danio rerio
 XRN1ENSGALG00000002706Gallus gallus
 XRN1ENSG00000114127Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004859  Putative 5-3 exonuclease
 IPR016494  5"-3" exoribonuclease 1
 IPR027073  5"-3" exoribonuclease


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0016075 rRNA catabolic process IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0071028 nuclear mRNA surveillance IEA
 biological_processGO:0071044 histone mRNA catabolic process IEA
 biological_processGO:0071409 cellular response to cycloheximide IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1905795 cellular response to puromycin IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004534 5"-3" exoribonuclease activity IEA
 molecular_functionGO:0008409 5"-3" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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