ENSMUSG00000032469


Mus musculus

Features
Gene ID: ENSMUSG00000032469
  
Biological name :Dbr1
  
Synonyms : Dbr1 / Lariat debranching enzyme / Q923B1
  
Possible biological names infered from orthology : debranching RNA lariats 1 / Q9UK59
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 99575799
Gene end: 99584501
  
Corresponding Affymetrix probe sets: 10588121 (MoGene1.0st)   1451641_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119924
Ensembl peptide - ENSMUSP00000115203
Ensembl peptide - ENSMUSP00000115978
Ensembl peptide - ENSMUSP00000070991
Ensembl peptide - ENSMUSP00000114670
Ensembl peptide - ENSMUSP00000115074
NCBI entrez gene - 83703     See in Manteia.
MGI - MGI:1931520
RefSeq - XM_006511563
RefSeq - NM_031403
RefSeq Peptide - NP_113580
swissprot - F6ZYX6
swissprot - F6S2R9
swissprot - F6UCV1
swissprot - Q923B1
swissprot - F6SDN8
swissprot - D3YXA2
Ensembl - ENSMUSG00000032469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dbr1ENSDARG00000056923Danio rerio
 DBR1ENSGALG00000043797Gallus gallus
 DBR1ENSG00000138231Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR007708  Lariat debranching enzyme, C-terminal
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000375 RNA splicing, via transesterification reactions IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0008419 RNA lariat debranching enzyme activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004816 abnormal class switch recombination "anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dio3tm1Dmst/Dio3tm1Dmst,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * DBA

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Dio3tm1Dmst/Dio3tm1Dmst,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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