ENSMUSG00000032623


Mus musculus

Features
Gene ID: ENSMUSG00000032623
  
Biological name :Oas1d
  
Synonyms : Inactive 2-5-oligoadenylate synthase 1D / Oas1d / Q8VI95
  
Possible biological names infered from orthology : 2-5-oligoadenylate synthetase 1 / OAS1 / P00973
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 120914536
Gene end: 120921652
  
Corresponding Affymetrix probe sets: 10525179 (MoGene1.0st)   1416847_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048054
NCBI entrez gene - 100535     See in Manteia.
MGI - MGI:2140770
RefSeq - NM_133893
RefSeq Peptide - NP_598654
swissprot - Q8VI95
Ensembl - ENSMUSG00000032623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OAS1ENSG00000089127Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Oas1e / Mus musculus 2-5 oligoadenylate synthetase 1E (Oas1e), transcript variant 1, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686782
Oas1c / Q924S2 / Inactive 2-5 oligoadenylate synthetase 1C / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116672
Oas1f / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005376568
Oas1h / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116862
Oas1a / P11928 / 2-5-oligoadenylate synthase 1A / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005277656
Oas1g / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686156
Oas3 / Q8VI93 / 2-5-oligoadenylate synthase 3 / Q9Y6K5* / 2-5-oligoadenylate synthetase 3*ENSMUSG0000003266140
Oas2 / E9Q9A9 / Mus musculus 2-5 oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA. / P29728* / 2-5-oligoadenylate synthetase 2*ENSMUSG0000003269040
Oas1b / Mus musculus 2-5 oligoadenylate synthetase 1B (Oas1b), transcript variant 1, coding, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000002960537
Oasl2 / Q9Z2F2 / 2-5-oligoadenylate synthase-like protein 2 ENSMUSG0000002956133
Oasl1 / Q8VI94 / 2-5-oligoadenylate synthase-like protein 1 / OASL* / Q15646* / 2-5-oligoadenylate synthetase like*ENSMUSG0000004182731


Protein motifs (from Interpro)
Interpro ID Name
 IPR006116  2-5-oligoadenylate synthetase, N-terminal
 IPR018952  2"-5"-oligoadenylate synthetase 1, domain 2/C-terminal
 IPR026774  2"-5"-oligoadenylate synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001542 ovulation from ovarian follicle IMP
 biological_processGO:0006955 immune response IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0004857 enzyme inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001131 abnormal ovarian follicles "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

 MP:0002680 decreased number of corpora lutea "fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

 MP:0003355 reduced ovulation "reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Numbtm1Ynj/Numbtm1Ynj,Numbltm1Wmz/Numbltm1Wmz
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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