ENSMUSG00000052776


Mus musculus

Features
Gene ID: ENSMUSG00000052776
  
Biological name :Oas1a
  
Synonyms : 2-5-oligoadenylate synthase 1A / Oas1a / P11928
  
Possible biological names infered from orthology : 2-5-oligoadenylate synthetase 1 / OAS1 / P00973
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 120896256
Gene end: 120907521
  
Corresponding Affymetrix probe sets: 10533246 (MoGene1.0st)   10533256 (MoGene1.0st)   1424775_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079198
NCBI entrez gene - 246730     See in Manteia.
MGI - MGI:2180860
RefSeq - NM_145211
RefSeq - XM_006530330
RefSeq Peptide - NP_660212
swissprot - P11928
Ensembl - ENSMUSG00000052776
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OAS1ENSG00000089127Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Oas1g / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686196
Oas1f / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005376563
Oas1c / Q924S2 / Inactive 2-5 oligoadenylate synthetase 1C / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116660
Oas1h / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116857
Oas1d / Q8VI95 / Inactive 2-5-oligoadenylate synthase 1D / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000003262355
Oas1e / Mus musculus 2-5 oligoadenylate synthetase 1E (Oas1e), transcript variant 1, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686754
Oas3 / Q8VI93 / 2-5-oligoadenylate synthase 3 / Q9Y6K5* / 2-5-oligoadenylate synthetase 3*ENSMUSG0000003266149
Oas2 / E9Q9A9 / Mus musculus 2-5 oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA. / P29728* / 2-5-oligoadenylate synthetase 2*ENSMUSG0000003269048
Oas1b / Mus musculus 2-5 oligoadenylate synthetase 1B (Oas1b), transcript variant 1, coding, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000002960546
Oasl2 / Q9Z2F2 / 2-5-oligoadenylate synthase-like protein 2 ENSMUSG0000002956140
Oasl1 / Q8VI94 / 2-5-oligoadenylate synthase-like protein 1 / OASL* / Q15646* / 2-5-oligoadenylate synthetase like*ENSMUSG0000004182737


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR006116  2-5-oligoadenylate synthetase, N-terminal
 IPR006117  2-5-oligoadenylate synthetase, conserved site
 IPR018952  2"-5"-oligoadenylate synthetase 1, domain 2/C-terminal
 IPR026774  2"-5"-oligoadenylate synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006164 purine nucleotide biosynthetic process IDA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0048525 negative regulation of viral process IDA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001730 2"-5"-oligoadenylate synthetase activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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