ENSMUSG00000066861


Mus musculus

Features
Gene ID: ENSMUSG00000066861
  
Biological name :Oas1g
  
Synonyms : Oas1g
  
Possible biological names infered from orthology : 2-5-oligoadenylate synthetase 1 / OAS1 / P00973
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 120876142
Gene end: 120887613
  
Corresponding Affymetrix probe sets: 10533246 (MoGene1.0st)   1424775_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000083555
Ensembl peptide - ENSMUSP00000124597
NCBI entrez gene - 23960     See in Manteia.
MGI - MGI:97429
RefSeq - NM_011852
RefSeq Peptide - NP_035982
swissprot - Q05BJ7
swissprot - Q8K469
Ensembl - ENSMUSG00000066861
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OAS1ENSG00000089127Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Oas1a / P11928 / 2-5-oligoadenylate synthase 1A / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005277696
Oas1f / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000005376562
Oas1c / Q924S2 / Inactive 2-5 oligoadenylate synthetase 1C / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116659
Oas1h / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000000116857
Oas1d / Q8VI95 / Inactive 2-5-oligoadenylate synthase 1D / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000003262355
Oas1e / Mus musculus 2-5 oligoadenylate synthetase 1E (Oas1e), transcript variant 1, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000006686755
Oas3 / Q8VI93 / 2-5-oligoadenylate synthase 3 / Q9Y6K5* / 2-5-oligoadenylate synthetase 3*ENSMUSG0000003266150
Oas2 / E9Q9A9 / Mus musculus 2-5 oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA. / P29728* / 2-5-oligoadenylate synthetase 2*ENSMUSG0000003269048
Oas1b / Mus musculus 2-5 oligoadenylate synthetase 1B (Oas1b), transcript variant 1, coding, mRNA. / OAS1* / P00973* / 2-5-oligoadenylate synthetase 1*ENSMUSG0000002960546
Oasl2 / Q9Z2F2 / 2-5-oligoadenylate synthase-like protein 2 ENSMUSG0000002956140
Oasl1 / Q8VI94 / 2-5-oligoadenylate synthase-like protein 1 / OASL* / Q15646* / 2-5-oligoadenylate synthetase like*ENSMUSG0000004182737


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR006116  2-5-oligoadenylate synthetase, N-terminal
 IPR006117  2-5-oligoadenylate synthetase, conserved site
 IPR018952  2"-5"-oligoadenylate synthetase 1, domain 2/C-terminal
 IPR026774  2"-5"-oligoadenylate synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0001730 2"-5"-oligoadenylate synthetase activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0004651 increased thoracic vertebrae number "increased number of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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