ENSMUSG00000033009


Mus musculus

Features
Gene ID: ENSMUSG00000033009
  
Biological name :Ogfod1
  
Synonyms : Ogfod1 / Prolyl 3-hydroxylase OGFOD1 / Q3U0K8
  
Possible biological names infered from orthology : 2-oxoglutarate and iron dependent oxygenase domain containing 1 / Q8N543
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C5
Gene start: 94037198
Gene end: 94067921
  
Corresponding Affymetrix probe sets: 10573998 (MoGene1.0st)   1435025_at (Mouse Genome 430 2.0 Array)   1439776_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000051430
Ensembl peptide - ENSMUSP00000090991
Ensembl peptide - ENSMUSP00000105183
NCBI entrez gene - 270086     See in Manteia.
MGI - MGI:2442978
RefSeq - XM_006531054
RefSeq - NM_001093757
RefSeq - NM_177767
RefSeq - XM_006531053
RefSeq Peptide - NP_808435
RefSeq Peptide - NP_001087226
swissprot - Q3U0K8
swissprot - D3YTU2
Ensembl - ENSMUSG00000033009
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ogfod1ENSDARG00000036061Danio rerio
 ENSGALG00000003071Gallus gallus
 OGFOD1ENSG00000087263Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR019601  Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006449 regulation of translational termination ISO
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0018126 protein hydroxylation ISO
 biological_processGO:0019511 peptidyl-proline hydroxylation ISO
 biological_processGO:0034063 stress granule assembly ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0031543 peptidyl-proline dioxygenase activity ISO
 molecular_functionGO:0031544 peptidyl-proline 3-dioxygenase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000559 abnormal femur morphology "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nsun2tm1a(EUCOMM)Wtsi/Nsun2tm1a(EUCOMM)Wtsi
Genetic Background: B6JTyr;B6N-Nsun2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0001191 abnormal skin condition "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nsun2tm1a(EUCOMM)Wtsi/Nsun2tm1a(EUCOMM)Wtsi
Genetic Background: B6JTyr;B6N-Nsun2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cnot3tm1.1Tya/Cnot3+,Lepob/Lepob
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0004151 hypoferremia "less than the normal concentration of this metallic element in the blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsun2tm1a(EUCOMM)Wtsi/Nsun2tm1a(EUCOMM)Wtsi
Genetic Background: B6JTyr;B6N-Nsun2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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