MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0000222 | decreased neutrophil count | "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0000352 | decreased cell proliferation | "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0000358 | abnormal cell content/ morphology | "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ero1lbGt(P077G11)Wrst/Ero1lbGt(P077G11)Wrst Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg,Pggt1btm1Mbrg/Pggt1btm1Mbrg,Tg(KRT14-cre)1Amc/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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MP:0000382 | underdeveloped hair follicles | "arrest of or retarded differentiation of the epidermal invaginations from which the hair shaft develops" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0000383 | abnormal hair follicle orientation | "misaligned hair follicles; hair follicles that do not orient in a typical pattern" [J:47620] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0000692 | small spleen | "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0001218 | thin epidermis | "reduced thickness of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg,Pggt1btm1Mbrg/Pggt1btm1Mbrg,Tg(KRT14-cre)1Amc/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0001545 | abnormal hematopoietic system physiology | "anomalous function of the fluid and/or its suspended elements that circulate(s) through the heart, arteries, capillaries, and veins" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0001675 | abnormal ectoderm development | "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fntbtm1Bbd/Fntbtm1Bbd,Krastm1Bbd/Kras+,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0002027 | lung adenocarcinoma | "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0002048 | lung adenoma | "benign epithelial neoplasm of the lung" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631] |
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Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0002655 | abnormal keratinocyte morphology | "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0002908 | delayed wound healing | "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037] |
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0002965 | hyperalbuminemia | "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0003077 | abnormal cell cycle | "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266] |
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Allelic Composition: Ero1lbGt(P077G11)Wrst/Ero1lbGt(P077G11)Wrst Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0003447 | reduced tumor growth/size | "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0004502 | decreased incidence of chemically-induced tumors | "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1Bbd/Fntbtm1.1Bbd,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0005013 | increased lymphocyte number | "greater than normal white blood cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0005501 | abnormal skin physiology | "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg,Pggt1btm1Mbrg/Pggt1btm1Mbrg,Tg(KRT14-cre)1Amc/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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MP:0005630 | increased lung weight | "greater than the normal state of the physical heaviness of the lung" [RGD:Rat Genome Database submission] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0006382 | abnormal lung epithelium morphology | "any structural anomaly of the epithelial layer of the lung" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0008014 | lung tumor | "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0008714 | lung carcinoma | "a malignant neoplasm of the ling, arising from epithelial cells, usually glandular or squamous" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+,Pggt1btm1Mbrg/Pggt1btm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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MP:0009584 | decreased keratinocyte proliferation | "reduction in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0010068 | decreased red blood cell distribution width | "lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0010123 | increased bone mineral content | "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Fntbtm1Bbd/Fntbtm1Bbd,Krastm1Bbd/Kras+,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H
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MP:0011195 | increased hair follicle apoptosis | "greater than expected levels of programmed cell death of cells in the epidermis from which the hair shaft develops" [MGI:mnk] |
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Allelic Composition: Ikzf1plstc/Ikzf1tm2Kge Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6JSfdAnu
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MP:0011704 | decreased fibroblast proliferation | "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith] |
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Allelic Composition: Ero1lbGt(P077G11)Wrst/Ero1lbGt(P077G11)Wrst Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.1Mbrg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012113 | decreased inner cell mass proliferation | |
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Allelic Composition: Fntbtm1Bbd/Fntbtm1Bbd,Krastm1Bbd/Kras+,Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
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MP:0013501 | increased fibroblast apoptosis | "increase in the timing or the number of fibroblast cells undergoing programmed cell death" [MGI:csmith] |
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Allelic Composition: Fntbtm1.1Mbrg/Fntbtm1.2Mbrg,Krastm4Tyj/Kras+ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
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