ENSMUSG00000033502


Mus musculus

Features
Gene ID: ENSMUSG00000033502
  
Biological name :Cdc14a
  
Synonyms : Cdc14a / Dual specificity protein phosphatase CDC14A / Q6GQT0
  
Possible biological names infered from orthology : cell division cycle 14A / Q9UNH5
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 116272553
Gene end: 116424032
  
Corresponding Affymetrix probe sets: 10501629 (MoGene1.0st)   1436913_at (Mouse Genome 430 2.0 Array)   1443184_at (Mouse Genome 430 2.0 Array)   1446493_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087950
Ensembl peptide - ENSMUSP00000102100
Ensembl peptide - ENSMUSP00000142479
NCBI entrez gene - 229776     See in Manteia.
MGI - MGI:2442676
RefSeq - XM_017319563
RefSeq - NM_001080818
RefSeq - NM_001173553
RefSeq - XM_006501419
RefSeq - XM_006501420
RefSeq - XM_011240108
RefSeq - XM_011240109
RefSeq Peptide - NP_001074287
RefSeq Peptide - NP_001167024
swissprot - Q6GQT0
swissprot - A0A0G2JDS3
Ensembl - ENSMUSG00000033502
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc14aaENSDARG00000013858Danio rerio
 cdc14abENSDARG00000057016Danio rerio
 CDC14AENSGALG00000005248Gallus gallus
 CDC14AENSG00000079335Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdc14b / Q6PFY9 / Dual specificity protein phosphatase CDC14B / O60729* / cell division cycle 14B*ENSMUSG0000003310241
Dusp23 / Q6NT99 / Dual specificity protein phosphatase 23 / Q9BVJ7* / dual specificity phosphatase 23*ENSMUSG000000265446


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR026068  Dual specificity protein phosphatase CDC14A
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029260  Dual specificity/tyrosine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007096 regulation of exit from mitosis IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0051256 mitotic spindle midzone assembly IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:0071850 mitotic cell cycle arrest IBA
 cellular_componentGO:0000922 spindle pole IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060091 kinocilium IEA
 cellular_componentGO:0072686 mitotic spindle IBA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IBA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000042688 Mapk6 / Q61532 / Mitogen-activated protein kinase 6 / Q16659*  / reaction / complex






 

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