ENSMUSG00000033760


Mus musculus

Features
Gene ID: ENSMUSG00000033760
  
Biological name :Rbm4b
  
Synonyms : Q8VE92 / Rbm4b / RNA-binding protein 4B
  
Possible biological names infered from orthology : Q9BQ04 / RNA binding motif protein 4B
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 4756543
Gene end: 4767065
  
Corresponding Affymetrix probe sets: 10460461 (MoGene1.0st)   1430032_at (Mouse Genome 430 2.0 Array)   1431113_at (Mouse Genome 430 2.0 Array)   1452112_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038256
Ensembl peptide - ENSMUSP00000138146
NCBI entrez gene - 66704     See in Manteia.
MGI - MGI:1913954
RefSeq - XM_006531826
RefSeq - NM_025717
RefSeq - XM_006531823
RefSeq - XM_006531824
RefSeq - XM_006531825
RefSeq Peptide - NP_079993
swissprot - Q8VE92
swissprot - S4R1A6
Ensembl - ENSMUSG00000033760
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6IQ97ENSDARG00000036386Danio rerio
 rbm4.2ENSDARG00000055080Danio rerio
 rbm4.3ENSDARG00000022129Danio rerio
 RBM4BENSG00000173914Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rbm4 / Q8C7Q4 / RNA binding motif protein 4 / Q9BWF3*ENSMUSG0000009493687
Gm21992 / RBM4* / Q9BWF3* / RNA binding motif protein 4*ENSMUSG0000009637087
Rbm14 / Q8C2Q3 / RNA-binding protein 14 / Q96PK6* / RNA binding motif protein 14*ENSMUSG0000000645632


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR001878  Zinc finger, CCHC-type
 IPR034897  RBM4, RNA recognition motif 1
 IPR034898  RBM4, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006417 regulation of translation IDA
 biological_processGO:0007623 circadian rhythm IDA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0032922 circadian regulation of gene expression IDA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

 MP:0009172 small pancreatic islets "decrease in the size of the clusters of hormone-producing cells that are scattered throughout the pancreas" [MA:0000127, MESH:A03.734.414]
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Allelic Composition: Atxn2tm2.1Geno/Atxn2tm2.1Geno
Genetic Background: B6.129S2-Atxn2tm2.1Geno

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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