ENSMUSG00000034321


Mus musculus

Features
Gene ID: ENSMUSG00000034321
  
Biological name :Exosc1
  
Synonyms : Exosc1 / Exosome complex component CSL4 / Q9DAA6
  
Possible biological names infered from orthology : exosome component 1 / Q9Y3B2
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 41922980
Gene end: 41933314
  
Corresponding Affymetrix probe sets: 10467688 (MoGene1.0st)   1432052_at (Mouse Genome 430 2.0 Array)   1452012_a_at (Mouse Genome 430 2.0 Array)   1453359_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074756
Ensembl peptide - ENSMUSP00000107751
NCBI entrez gene - 66583     See in Manteia.
MGI - MGI:1913833
RefSeq - NM_001320233
RefSeq - NM_025644
RefSeq - XM_011247313
RefSeq - NM_001164561
RefSeq - NM_001320231
RefSeq - NM_001320232
RefSeq - XM_011247312
RefSeq Peptide - NP_001307161
RefSeq Peptide - NP_001307162
RefSeq Peptide - NP_079920
RefSeq Peptide - NP_001158033
RefSeq Peptide - NP_001307160
swissprot - Q9DAA6
Ensembl - ENSMUSG00000034321
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exosc1ENSDARG00000059841Danio rerio
 EXOSC1ENSGALG00000039917Gallus gallus
 EXOSC1ENSG00000171311Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012340  Nucleic acid-binding, OB-fold
 IPR019495  Exosome complex component CSL4
 IPR022967  RNA-binding domain, S1
 IPR025721  Exosome complex component, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006396 RNA processing ISO
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IBA
 cellular_componentGO:0000178 exosome (RNase complex) ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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