Manteia - Molecule gene

ENSMUSG00000034675

Mus musculus

Features

Gene ID:	ENSMUSG00000034675

Biological name :	Dbn1

Synonyms :	Dbn1 / Drebrin / Q9QXS6

Possible biological names infered from orthology :	drebrin 1 / Q16643

Species:	Mus musculus

Chr. number:	13
Strand:	-1
Band:	B1
Gene start:	55473429
Gene end:	55488111

Corresponding Affymetrix probe sets:	10409464 (MoGene1.0st) 1426024_a_at (Mouse Genome 430 2.0 Array) 1451734_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000021950 Ensembl peptide - ENSMUSP00000105547 Ensembl peptide - ENSMUSP00000105549 Ensembl peptide - ENSMUSP00000122574 NCBI entrez gene - 56320 See in Manteia. MGI - MGI:1931838 RefSeq - XM_006517305 RefSeq - NM_001177371 RefSeq - NM_001177372 RefSeq - NM_019813 RefSeq Peptide - NP_062787 RefSeq Peptide - NP_001170842 RefSeq Peptide - NP_001170843 swissprot - A0A0R4J1E3 swissprot - F7CPL2 swissprot - Q3TRK3 swissprot - Q9QXS6 Ensembl - ENSMUSG00000034675

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
dbn1	ENSDARG00000069113	Danio rerio
DBN1	ENSGALG00000033405	Gallus gallus
DBN1	ENSG00000113758	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Dbnl / Q62418 / Drebrin-like protein / Q9UJU6* / drebrin like*	ENSMUSG00000020476	21
Hcls1 / P49710 / Hematopoietic lineage cell-specific protein / P14317* / hematopoietic cell-specific Lyn substrate 1*	ENSMUSG00000022831	10
Cttn / Q60598 / cortactin / Q14247*	ENSMUSG00000031078	9

Protein motifs (from Interpro)

Interpro ID	Name
IPR002108	Actin-depolymerising factor homology domain
IPR011989	Armadillo-like helical
IPR015943	WD40/YVTN repeat-like-containing domain superfamily
IPR028438	Drebrin
IPR029006	ADF-H/Gelsolin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007015	actin filament organization	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0007399	nervous system development	IEA
biological_process	GO:0010643	cell communication by chemical coupling	IMP
biological_process	GO:0010644	cell communication by electrical coupling	IMP
biological_process	GO:0030154	cell differentiation	IEA
biological_process	GO:0032507	maintenance of protein location in cell	IMP
biological_process	GO:0048699	generation of neurons	IEP
biological_process	GO:0061351	neural precursor cell proliferation	IEP
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
cellular_component	GO:0005886	plasma membrane	IDA
cellular_component	GO:0005911	cell-cell junction	IDA
cellular_component	GO:0005921	gap junction	IDA
cellular_component	GO:0005938	cell cortex	IEA
cellular_component	GO:0015629	actin cytoskeleton	IDA
cellular_component	GO:0016020	membrane	IDA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0030426	growth cone	IEA
cellular_component	GO:0042995	cell projection	IEA
molecular_function	GO:0003779	actin binding	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005522	profilin binding	ISS
molecular_function	GO:0045296	cadherin binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000137	abnormal vertebrae morphology	"malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Daam2^{tm1b(KOMP)Wtsi}/Daam2^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Daam2^{tm1b(KOMP)Wtsi}/Wtsi
MP:0000183	decreased circulating LDL cholesterol level	"less than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000186	decreased circulating HDL cholesterol level	"lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000195	hypocalcemia	"subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000274	enlarged heart	"increase over normal size of the heart" [J:29971]	Show Allelic Composition: Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ Genetic Background: C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/J
MP:0000602	enlarged sinusoidal spaces	"larger than normal sized cavities in the liver " [J:23170]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000783	abnormal forebrain morphology	"malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000787	abnormal telencephalon morphology	"any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0000807	abnormal hippocampus morphology	"absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]	Show Allelic Composition: Atg5^tm1Myok/Atg5^tm1Myok,Tg(Pomc1-cre)1Gsb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0001566	hyperphosphatemia	"abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Daam2^{tm1b(KOMP)Wtsi}/Daam2^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Daam2^{tm1b(KOMP)Wtsi}/Wtsi
MP:0001697	abnormal embryo size	"anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc
MP:0001900	impaired synaptic plasticity	"decreased or inability of the nervous system to change its reactivity as a result of successive activations " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Atg5^tm1Myok/Atg5^tm1Myok,Tg(Pomc1-cre)1Gsb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
MP:0002591	decreased mean corpuscular volume	"less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0002833	increased heart weight	"greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ Genetic Background: C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/J
MP:0002942	decreased circulating alanine transaminase level	"decreased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0003019	increased circulating chloride level	"elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0003345	decreased number of ribs	"fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Daam2^{tm1b(KOMP)Wtsi}/Daam2^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Daam2^{tm1b(KOMP)Wtsi}/Wtsi
MP:0003795	abnormal bone structure		Show Allelic Composition: Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ Genetic Background: C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/J
MP:0003960	increased lean body mass	"more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Crb2^{tm1a(KOMP)Wtsi}/Crb2⁺ Genetic Background: C57BL/6N-Crb2^{tm1a(KOMP)Wtsi}/Wtsi Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay
MP:0004647	decreased lumbar vertebrae number	"reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0005179	decreased total circulating cholesterol level	"less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0005419	hypoalbuminemia	"blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
MP:0005553	increased circulating creatinine level	"greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Dixdc1^{tm1.1(KOMP)Vlcg}/Dixdc1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Dixdc1^{tm1.1(KOMP)Vlcg}/J
MP:0005567	decreased circulating total protein level	"less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0005632	decreased circulating aspartate transaminase level	"less than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0008026	abnormal brain white matter morphology	"any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0008128	abnormal brain internal capsule morphology	"any structural anomaly of the area of white matter in the brain that lies between the lenticular and caudate nuclei, and contains a group of myelinated ascending and descending axonal fiber tracts that connects the cerebral cortex to the brain stem and spinal cord" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0008922	abnormal cervical rib	"alternate location or appearance of a rare supernumerary rib commonly articulating with the seventh cervical vertebrae (above the normal first rib) but not reaching the sternum anteriorly" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0008935	decreased mean platelet volume	"reduced average content of platelet cells over normal" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
MP:0009456	impaired cued conditioning behavior	"decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light flash)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pkdcc^tm1.1Mask/Pkdcc^tm1.1Mask Genetic Background: involves: C57BL/6 * CBA * FVB/N
MP:0009936	abnormal dendritic spine morphology	"any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Atg5^tm1Myok/Atg5^tm1Myok,Tg(Pomc1-cre)1Gsb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N Allelic Composition: Dbn1^tm1.1Lbc/Dbn1⁺ Genetic Background: B6.Cg-Dbn1^tm1.1Lbc
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1a(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1a(KOMP)Wtsi}/Wtsi Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J
MP:0010067	increased red blood cell distribution width	"higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
MP:0010088	decreased circulating fructosamine level	"decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ics Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Rbrc
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Cp^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Bay Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/H Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
MP:0011396	abnormal sleep behavior	"any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J
MP:0011965	decreased total retina thickness	"decreased width of the retina through the center plane" [MGI:csmith]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/J
MP:0013278	decreased fasted circulating glucose level	"reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1⁺ Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Ucd
MP:0013824	abnormal hypoglossal canal morphology	"any structural anomaly of the bony canal in the occipital bone through which the hypoglossal nerve emerges from the skull" [ISBN:0683400088]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
MP:0013826	absent hypoglossal canal	"absence of the bony canal in the occipital bone through which the hypoglossal nerve emerges from the skull" [ISBN:0683400088]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
MP:0013834	thin hypoglossal nerve	"slender appearance of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
MP:0013835	absent hypoglossal nerve	"absence of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
MP:0013915	abnormal brachial plexus formation	"abnormal formation of the arrangement of nerve fibers, running from the spine, formed by the ventral rami of the lower cervical and upper thoracic nerve root, specifically from below the fifth cervical vertebra to above the first thoracic vertebra" [UBERON:0001814]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi
MP:0014017	abnormal Wolffian duct connection	"aberrant attachment or incomplete connection of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) to the cloaca " [ISBN:0-683-40008-8]	Show Allelic Composition: Dbn1^{tm1b(KOMP)Wtsi}/Dbn1^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Dbn1^{tm1b(KOMP)Wtsi}/Wtsi

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr