ENSG00000113758


Homo sapiens

Features
Gene ID: ENSG00000113758
  
Biological name :DBN1
  
Synonyms : DBN1 / drebrin 1 / Q16643
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.3
Gene start: 177456608
Gene end: 177474401
  
Corresponding Affymetrix probe sets: 202806_at (Human Genome U133 Plus 2.0 Array)   217025_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308532
Ensembl peptide - ENSP00000377195
Ensembl peptide - ENSP00000425546
Ensembl peptide - ENSP00000423208
Ensembl peptide - ENSP00000422854
Ensembl peptide - ENSP00000421465
Ensembl peptide - ENSP00000292385
NCBI entrez gene - 1627     See in Manteia.
OMIM - 126660
RefSeq - XM_006714826
RefSeq - XM_005265827
RefSeq - XM_017009139
RefSeq - XM_011534447
RefSeq - NM_004395
RefSeq - NM_080881
RefSeq - XM_017009140
RefSeq - XM_011534446
RefSeq Peptide - NP_543157
RefSeq Peptide - NP_004386
swissprot - Q16643
swissprot - D6RFI1
swissprot - D6R9Q9
swissprot - D6R9W4
swissprot - D6RCR4
Ensembl - ENSG00000113758
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dbn1ENSDARG00000069113Danio rerio
 DBN1ENSGALG00000033405Gallus gallus
 Dbn1ENSMUSG00000034675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DBNL / Q9UJU6 / drebrin likeENSG0000013627921
CTTN / Q14247 / cortactinENSG0000008573311
HCLS1 / P14317 / hematopoietic cell-specific Lyn substrate 1ENSG0000018035311


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR028438  Drebrin
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010643 cell communication by chemical coupling IEA
 biological_processGO:0010644 cell communication by electrical coupling IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032507 maintenance of protein location in cell IEA
 biological_processGO:0048168 regulation of neuronal synaptic plasticity NAS
 biological_processGO:0048699 generation of neurons IEA
 biological_processGO:0050773 regulation of dendrite development NAS
 biological_processGO:0061351 neural precursor cell proliferation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0015629 actin cytoskeleton ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite NAS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0030863 cortical cytoskeleton TAS
 cellular_componentGO:0042641 actomyosin NAS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005522 profilin binding ISS
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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