ENSMUSG00000034706


Mus musculus

Features
Gene ID: ENSMUSG00000034706
  
Biological name :Dnaic2
  
Synonyms : A2AC93 / Dnaic2 / Dynein intermediate chain 2, axonemal
  
Possible biological names infered from orthology : DNAI2 / dynein axonemal intermediate chain 2 / Q9GZS0
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 114727408
Gene end: 114757889
  
Corresponding Affymetrix probe sets: 10382393 (MoGene1.0st)   1436296_x_at (Mouse Genome 430 2.0 Array)   1445408_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065787
Ensembl peptide - ENSMUSP00000090126
Ensembl peptide - ENSMUSP00000114700
NCBI entrez gene - 432611     See in Manteia.
MGI - MGI:2685574
RefSeq - XM_006533663
RefSeq - NM_001034878
RefSeq - XM_006533660
RefSeq - XM_006533661
RefSeq - XM_006533662
RefSeq Peptide - NP_001030050
swissprot - R4GML5
swissprot - A2AC93
Ensembl - ENSMUSG00000034706
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnai2bENSDARG00000074081Danio rerio
 DNAI2ENSGALG00000004495Gallus gallus
 DNAI2ENSG00000171595Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wdr34 / WD repeat domain 34 / Q96EX3*ENSMUSG0000003971517
Wdr78 / E9PYY5 / WD repeat domain 78 / Q5VTH9*ENSMUSG0000003512616
Dnaic1 / Q8C0M8 / Dynein intermediate chain 1, axonemal / DNAI1* / Q9UI46* / dynein axonemal intermediate chain 1*ENSMUSG0000006132216
O88487 / Dync1i2 / Mus musculus dynein cytoplasmic 1 intermediate chain 2 (Dync1i2), transcript variant 9, mRNA. / Q13409* / dynein cytoplasmic 1 intermediate chain 2*ENSMUSG0000002701215
O88485 / Dync1i1 / Cytoplasmic dynein 1 intermediate chain 1 / O14576* / dynein cytoplasmic 1 intermediate chain 1*ENSMUSG0000002975715


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement ISO
 biological_processGO:0007368 determination of left/right symmetry ISO
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0036158 outer dynein arm assembly ISO
 biological_processGO:0060271 cilium assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex ISO
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme ISO
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036126 sperm flagellum ISO
 cellular_componentGO:0036157 outer dynein arm ISO
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045504 dynein heavy chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002766 situs inversus "lateral transposition of the viscera of the thorax and abdomen, sometimes incomplete" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Frem2b2b3270Clo/Frem2b2b3270Clo
Genetic Background: C57BL/6J-Frem2b2b3270Clo

 MP:0011252 situs inversus totalis "the complete right to left reversal (transposition) of the thoracic and abdominal organs, including the heart (dextrocardia)" [MGI:csmith]
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Allelic Composition: Frem2b2b3270Clo/Frem2b2b3270Clo
Genetic Background: C57BL/6J-Frem2b2b3270Clo

 MP:0011649 immotile respiratory cilia "failure of the multiple epithelial tiny, motile hair-like projections of the repiratory tract epithelium to beat with a characteristic whip-like pattern in order to promote transport of fluids and other cells across the epithelium of the respiratory tract" [MGI:csmith]
Show

Allelic Composition: Frem2b2b3270Clo/Frem2b2b3270Clo
Genetic Background: C57BL/6J-Frem2b2b3270Clo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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