ENSMUSG00000036466


Mus musculus

Features
Gene ID: ENSMUSG00000036466
  
Biological name :Megf11
  
Synonyms : Megf11 / Multiple epidermal growth factor-like domains protein 11 / Q80T91
  
Possible biological names infered from orthology : A6BM72 / multiple EGF like domains 11
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: C
Gene start: 64385626
Gene end: 64709205
  
Corresponding Affymetrix probe sets: 10586194 (MoGene1.0st)   1458015_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091349
Ensembl peptide - ENSMUSP00000120514
Ensembl peptide - ENSMUSP00000128672
Ensembl peptide - ENSMUSP00000065353
Ensembl peptide - ENSMUSP00000114035
NCBI entrez gene - 214058     See in Manteia.
MGI - MGI:1920951
RefSeq - XM_017313269
RefSeq - XM_006510988
RefSeq - XM_006510989
RefSeq - XM_006510991
RefSeq - XM_006510992
RefSeq - XM_017313268
RefSeq - NM_001134399
RefSeq - NM_172522
RefSeq - XM_006510984
RefSeq - XM_006510985
RefSeq - XM_006510986
RefSeq - XM_006510987
RefSeq Peptide - NP_001127871
RefSeq Peptide - NP_766110
swissprot - F6UPK0
swissprot - Q80T91
swissprot - E9Q918
Ensembl - ENSMUSG00000036466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 megf11ENSDARG00000062686Danio rerio
 MEGF11ENSGALG00000007631Gallus gallus
 A6BM72ENSG00000157890Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Megf10 / Q6DIB5 / Multiple epidermal growth factor-like domains protein 10 / Q96KG7* / multiple EGF like domains 10*ENSMUSG0000002459360
Pear1 / Q8VIK5 / platelet endothelial aggregation receptor 1 / Q5VY43*ENSMUSG0000002807341
Megf6 / multiple EGF like domains 6 / O75095*ENSMUSG0000005775133
Q5ND28 / Scarf1 / Scavenger receptor class F member 1 / Q14162*ENSMUSG0000003818819
P59222 / Scarf2 / Scavenger receptor class F member 2 / Q96GP6*ENSMUSG0000001201717
Egfem1 / Q8C088 / EGF-like and EMI domain-containing protein 1 ENSMUSG000000636008


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002049  Laminin EGF domain
 IPR011489  EMI domain
 IPR013032  EGF-like, conserved site
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0034109 homotypic cell-cell adhesion IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005240 abnormal amacrine cell morphology "anomalous structure of the interneurons of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp
Genetic Background: involves: 129S1/Sv

 MP:0006068 abnormal horizontal cell morphology "anomalous structure of the laterally interconnecting neurons in the outer plexiform layer" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp
Genetic Background: involves: 129S1/Sv

Allelic Composition: Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs,Megf11tm1a(EUCOMM)Wtsi/Megf11tm1a(EUCOMM)Wtsi
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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