ENSMUSG00000012017


Mus musculus

Features
Gene ID: ENSMUSG00000012017
  
Biological name :Scarf2
  
Synonyms : P59222 / Scarf2 / Scavenger receptor class F member 2
  
Possible biological names infered from orthology : Q96GP6
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A3
Gene start: 17797282
Gene end: 17808287
  
Corresponding Affymetrix probe sets: 10434105 (MoGene1.0st)   1434740_at (Mouse Genome 430 2.0 Array)   1438203_at (Mouse Genome 430 2.0 Array)   1438406_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000012161
NCBI entrez gene - 224024     See in Manteia.
MGI - MGI:1858430
RefSeq - XM_006522042
RefSeq - NM_153790
RefSeq Peptide - NP_722485
swissprot - P59222
swissprot - Q58A84
Ensembl - ENSMUSG00000012017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01077124.1ENSDARG00000114825Danio rerio
 SCARF2ENSGALG00000034560Gallus gallus
 Q96GP6ENSG00000244486Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5ND28 / Scarf1 / Scavenger receptor class F member 1 / Q14162*ENSMUSG0000003818833
Megf10 / Q6DIB5 / Multiple epidermal growth factor-like domains protein 10 / Q96KG7* / multiple EGF like domains 10*ENSMUSG0000002459324
Megf11 / Q80T91 / Multiple epidermal growth factor-like domains protein 11 / A6BM72* / multiple EGF like domains 11*ENSMUSG0000003646623
Megf6 / multiple EGF like domains 6 / O75095*ENSMUSG0000005775123
Pear1 / Q8VIK5 / platelet endothelial aggregation receptor 1 / Q5VY43*ENSMUSG0000002807322
Egfem1 / Q8C088 / EGF-like and EMI domain-containing protein 1 ENSMUSG000000636006


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002049  Laminin EGF domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR033327  Scavenger receptor class F member 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005044 scavenger receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0004357 long tibia "increased length of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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