ENSMUSG00000036880


Mus musculus

Features
Gene ID: ENSMUSG00000036880
  
Biological name :Acaa2
  
Synonyms : 3-ketoacyl-CoA thiolase, mitochondrial / Acaa2 / Q8BWT1
  
Possible biological names infered from orthology : acetyl-CoA acyltransferase 2 / P42765
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E2
Gene start: 74779197
Gene end: 74806207
  
Corresponding Affymetrix probe sets: 10456699 (MoGene1.0st)   1428145_at (Mouse Genome 430 2.0 Array)   1428146_s_at (Mouse Genome 430 2.0 Array)   1455061_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037348
NCBI entrez gene - 52538     See in Manteia.
MGI - MGI:1098623
RefSeq - NM_177470
RefSeq Peptide - NP_803421
swissprot - Q8BWT1
Ensembl - ENSMUSG00000036880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acaa2ENSDARG00000038881Danio rerio
 ACAA2ENSGALG00000031142Gallus gallus
 ACAA2ENSG00000167315Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acat2 / Q8CAY6 / acetyl-Coenzyme A acetyltransferase 2 / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000002383240
Acat3 / acetyl-Coenzyme A acetyltransferase 3 / ACAT2* / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000006248039
Acat1 / Q8QZT1 / Acetyl-CoA acetyltransferase, mitochondrial / P24752* / acetyl-CoA acetyltransferase 1*ENSMUSG0000003204738


Protein motifs (from Interpro)
Interpro ID Name
 IPR002155  Thiolase
 IPR016039  Thiolase-like
 IPR020610  Thiolase, active site
 IPR020613  Thiolase, conserved site
 IPR020615  Thiolase, acyl-enzyme intermediate active site
 IPR020616  Thiolase, N-terminal
 IPR020617  Thiolase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IEA
 biological_processGO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003988 acetyl-CoA C-acyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036880 Acaa2 / Q8BWT1 / 3-ketoacyl-CoA thiolase, mitochondrial / P42765* / acetyl-CoA acyltransferase 2*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr