Manteia

ENSMUSG00000036980

Mus musculus

Features

Gene ID:	ENSMUSG00000036980

Biological name :	Taf6

Synonyms :	Mus musculus TATA-box binding protein associated factor 6 (Taf6), transcript variant 4, mRNA. / Q62311 / Taf6

Possible biological names infered from orthology :	P49848 / TATA-box binding protein associated factor 6

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	G2
Gene start:	138178617
Gene end:	138187451

Corresponding Affymetrix probe sets:	10534990 (MoGene1.0st) 1418593_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000116512 Ensembl peptide - ENSMUSP00000106562 Ensembl peptide - ENSMUSP00000122534 Ensembl peptide - ENSMUSP00000138335 Ensembl peptide - ENSMUSP00000048016 Ensembl peptide - ENSMUSP00000106561 NCBI entrez gene - 21343 See in Manteia. MGI - MGI:109129 RefSeq - XM_017320786 RefSeq - NM_001356601 RefSeq - NM_001356602 RefSeq - NM_009315 RefSeq - XM_011240936 RefSeq - XM_011240937 RefSeq - XM_011240938 RefSeq - XM_011240939 RefSeq - XM_011240940 RefSeq - XM_017320785 RefSeq - NM_001356600 RefSeq Peptide - NP_033341 RefSeq Peptide - NP_001343529 RefSeq Peptide - NP_001343530 RefSeq Peptide - NP_001343531 swissprot - D3Z0T0 swissprot - S4R1R2 swissprot - D3Z4X5 swissprot - Q62311 swissprot - D3Z5H6 Ensembl - ENSMUSG00000036980

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Taf6l / Q8R2K4 / Q9CY24 / TATA-box binding protein associated factor 6 like / Q9Y6J9*	ENSMUSG00000003680	19

Protein motifs (from Interpro)

Interpro ID	Name
IPR004823	TATA box binding protein associated factor (TAF)
IPR009072	Histone-fold
IPR011442	TAF6, C-terminal HEAT repeat domain
IPR011989	Armadillo-like helical
IPR016024	Armadillo-type fold

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006352	DNA-templated transcription, initiation	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006367	transcription initiation from RNA polymerase II promoter	IEA
biological_process	GO:0008285	negative regulation of cell proliferation	ISO
biological_process	GO:0045786	negative regulation of cell cycle	IEA
biological_process	GO:0051090	regulation of DNA-binding transcription factor activity	IEA
cellular_component	GO:0000124	SAGA complex	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005669	transcription factor TFIID complex	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0032991	protein-containing complex	IEA
cellular_component	GO:0033276	transcription factor TFTC complex	IEA
cellular_component	GO:0046695	SLIK (SAGA-like) complex	IEA
cellular_component	GO:0071339	MLL1 complex	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0003700	DNA-binding transcription factor activity	IEA
molecular_function	GO:0005488	binding	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0017162	aryl hydrocarbon receptor binding	IEA
molecular_function	GO:0046982	protein heterodimerization activity	IEA

Pathways (from Reactome)

Pathway description

RNA Polymerase II Pre-transcription Events

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001415	increased exploration in new environment	"greater amount of time spent investigating new location" [J:28825]	Show Allelic Composition: Mthfd1^{tm2b(KOMP)Wtsi}/Mthfd1^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Mthfd1^{tm2b(KOMP)Wtsi}/Bay
MP:0006204	embryonic lethality before implantation	"death anytime after fertilization but before implantation (E0 to less than E4.5)" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Hsp90aa1^{Tg(Tyr)2396BOve}/Hsp90aa1^{Tg(Tyr)2396BOve} Genetic Background: FVB/N-Hsp90aa1^{Tg(Tyr)2396BOve}
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Mthfd1^{tm2b(KOMP)Wtsi}/Mthfd1^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Mthfd1^{tm2b(KOMP)Wtsi}/Bay
MP:0013292	embryonic lethality prior to organogenesis	"death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]	Show Allelic Composition: Mthfd1^{tm2b(KOMP)Wtsi}/Mthfd1^{tm2b(KOMP)Wtsi} Genetic Background: C57BL/6N-Mthfd1^{tm2b(KOMP)Wtsi}/Bay

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr