ENSMUSG00000037013


Mus musculus

Features
Gene ID: ENSMUSG00000037013
  
Biological name :Ss18
  
Synonyms : Q62280 / Ss18 / SS18, nBAF chromatin remodeling complex subunit
  
Possible biological names infered from orthology : Q15532
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: A1
Gene start: 14624198
Gene end: 14682914
  
Corresponding Affymetrix probe sets: 10457598 (MoGene1.0st)   1419360_a_at (Mouse Genome 430 2.0 Array)   1419361_at (Mouse Genome 430 2.0 Array)   1436257_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046320
Ensembl peptide - ENSMUSP00000047867
Ensembl peptide - ENSMUSP00000089673
NCBI entrez gene - 268996     See in Manteia.
MGI - MGI:107708
RefSeq - XM_006525948
RefSeq - NM_001161369
RefSeq - NM_001161370
RefSeq - NM_001161371
RefSeq - NM_009280
RefSeq Peptide - NP_001154843
RefSeq Peptide - NP_033306
RefSeq Peptide - NP_001154841
RefSeq Peptide - NP_001154842
swissprot - Q62280
swissprot - Q8BJJ6
swissprot - Q8BKL1
Ensembl - ENSMUSG00000037013
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ss18ENSDARG00000002970Danio rerio
 SS18ENSGALG00000015119Gallus gallus
 SS18ENSG00000141380Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BW22 / Ss18l1 / SS18, nBAF chromatin remodeling complex subunit like 1 / O75177* / SS18L1, nBAF chromatin remodeling complex subunit*ENSMUSG0000003908661
Q9D174 / Ss18l2 / SS18, nBAF chromatin remodeling complex subunit like 2 / Q9UHA2* / SS18 like 2*ENSMUSG0000003252610


Protein motifs (from Interpro)
Interpro ID Name
 IPR007726  SS18 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IDA
 biological_processGO:0000902 cell morphogenesis IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007010 cytoskeleton organization IDA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0042493 response to drug IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IDA
 biological_processGO:0097150 neuronal stem cell population maintenance IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0071564 npBAF complex IDA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001574 abnormal oxygen level "anomalous concentration of this gaseous element, essential for animal and plant life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001701 incomplete embryo turning "arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001711 abnormal placenta 
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001712 abnormal placental development "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0002824 abnormal chorioallantoic fusion "abnormal process of or failure of the formation of the membrane that forms the fetal portion of the placenta; derived from the fusion of the chorion and the allantois" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0003231 abnormal placental vasculature "malformation in the vessels of the placenta" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0003400 kinked neural tube "twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

Allelic Composition: Ss18tm1Adg/Ss18+
Genetic Background: involves: C57BL/6

 MP:0004560 abnormal chorionic plate morphology "any structural anomaly of the portion of the chorion from which chorionic villi develop that establish a connection with the endometrium, giving rise to the fetal portion of the mature placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Ss18tm1Adg/Ss18tm1Adg
Genetic Background: B6.Cg-Ss18tm1Adg

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Erbb3tm1Squ/Erbb3tm1Squ,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

Allelic Composition: Ss18tm1Adg/Ss18tm1Adg
Genetic Background: B6.Cg-Ss18tm1Adg

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ss18tm1Adg/Ss18+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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