ENSMUSG00000037935


Mus musculus

Features
Gene ID: ENSMUSG00000037935
  
Biological name :Smarce1
  
Synonyms : O54941 / Smarce1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  
Possible biological names infered from orthology : Q969G3
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 99209047
Gene end: 99231017
  
Corresponding Affymetrix probe sets: 10390768 (MoGene1.0st)   10527528 (MoGene1.0st)   10578391 (MoGene1.0st)   1422675_at (Mouse Genome 430 2.0 Array)   1422676_at (Mouse Genome 430 2.0 Array)   1430822_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099422
NCBI entrez gene - 57376     See in Manteia.
MGI - MGI:1927347
RefSeq - XM_011249158
RefSeq - NM_020618
RefSeq - XM_006533827
RefSeq - XM_006533828
RefSeq Peptide - NP_065643
swissprot - O54941
Ensembl - ENSMUSG00000037935
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smarce1ENSDARG00000016871Danio rerio
 SMARCE1ENSGALG00000003882Gallus gallus
 Q969G3ENSG00000073584Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR030089  SWI/SNF complex subunit BAF57
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006337 nucleosome disassembly IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0022008 neurogenesis IGI
 biological_processGO:0043044 ATP-dependent chromatin remodeling IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016514 SWI/SNF complex ISO
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 cellular_componentGO:0071564 npBAF complex IDA
 cellular_componentGO:0071565 nBAF complex IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008080 N-acetyltransferase activity IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Gabrg2tm1Spet/Gabrg2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ

Allelic Composition: Smarce1tm1Tich/Smarce1tm1Tich
Genetic Background: involves: 129

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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