ENSMUSG00000038296


Mus musculus

Features
Gene ID: ENSMUSG00000038296
  
Biological name :Galnt18
  
Synonyms : Galnt18 / Polypeptide N-acetylgalactosaminyltransferase 18 / Q8K1B9
  
Possible biological names infered from orthology : Q6P9A2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F1
Gene start: 111471661
Gene end: 111779977
  
Corresponding Affymetrix probe sets: 10566993 (MoGene1.0st)   1454780_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043636
Ensembl peptide - ENSMUSP00000102274
NCBI entrez gene - 233733     See in Manteia.
MGI - MGI:2446239
RefSeq - XM_006507658
RefSeq - NM_173739
RefSeq Peptide - NP_776100
swissprot - Q59J91
swissprot - Q8K1B9
Ensembl - ENSMUSG00000038296
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galnt18aENSDARG00000100889Danio rerio
 galnt18bENSDARG00000059438Danio rerio
 GALNT18ENSGALG00000005584Gallus gallus
 Q6P9A2ENSG00000110328Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7TT15 / Galnt17 / Polypeptide N-acetylgalactosaminyltransferase 17 / Q6IS24*ENSMUSG0000003404048
Galnt9 / polypeptide N-acetylgalactosaminyltransferase 9 / Q9HCQ5*ENSMUSG0000003331647
Q6P9S7 / Galnt10 / Polypeptide N-acetylgalactosaminyltransferase 10 / Q86SR1*ENSMUSG0000002052028
Q9D2N8 / Galnt15 / Polypeptide N-acetylgalactosaminyltransferase 15 / Q8N3T1*ENSMUSG0000002190326
Galntl6 / polypeptide N-acetylgalactosaminyltransferase like 6 / Q49A17*ENSMUSG0000009691426
Galnt7 / Q80VA0 / N-acetylgalactosaminyltransferase 7 / Q86SF2* / polypeptide N-acetylgalactosaminyltransferase 7*ENSMUSG0000003160825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000772  Ricin B, lectin domain
 IPR001173  Glycosyltransferase 2-like
 IPR029044  Nucleotide-diphospho-sugar transferases
 IPR035992  Ricin B-like lectins


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004653 polypeptide N-acetylgalactosaminyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0010067 increased red blood cell distribution width "higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0010087 increased circulating fructosamine level "increase in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0010088 decreased circulating fructosamine level "decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0012768 decreased KLRG1-positive NK cell number "decrease in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation" [MGI:Annie_Speak, PMID:19479342]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0013022 increased Ly6C high monocyte number "increase in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues" [MGI:Annie_Speak]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0013026 decreased Ly6C low monocyte number "decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes" [MGI:Annie_Speak]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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