ENSMUSG00000039254


Mus musculus

Features
Gene ID: ENSMUSG00000039254
  
Biological name :Pomt1
  
Synonyms : Pomt1 / Protein O-mannosyl-transferase 1 / Q8R2R1
  
Possible biological names infered from orthology : protein O-mannosyltransferase 1 / Q9Y6A1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 32236590
Gene end: 32255005
  
Corresponding Affymetrix probe sets: 10471337 (MoGene1.0st)   1424284_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038722
Ensembl peptide - ENSMUSP00000142212
Ensembl peptide - ENSMUSP00000118382
Ensembl peptide - ENSMUSP00000116543
Ensembl peptide - ENSMUSP00000116117
NCBI entrez gene - 99011     See in Manteia.
MGI - MGI:2138994
RefSeq - XM_006498474
RefSeq - NM_145145
RefSeq - XM_006498473
RefSeq Peptide - NP_660127
swissprot - B0R071
swissprot - D6RI46
swissprot - Q8R2R1
swissprot - B0R070
swissprot - A0A0A6YXZ7
Ensembl - ENSMUSG00000039254
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pomt1ENSDARG00000067670Danio rerio
 POMT1ENSGALG00000003757Gallus gallus
 POMT1ENSG00000130714Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pomt2 / Q8BGQ4 / Protein O-mannosyl-transferase 2 / Q9UKY4* / protein O-mannosyltransferase 2*ENSMUSG0000003412631


Protein motifs (from Interpro)
Interpro ID Name
 IPR003342  Glycosyl transferase family 39/83
 IPR016093  MIR motif
 IPR027005  Glycosyltransferase 39-like
 IPR032421  Protein O-mannosyl-transferase, C-terminal four TM domain
 IPR036300  Mir domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0035269 protein O-linked mannosylation IEA
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IBA
 biological_processGO:0097502 mannosylation IEA
 biological_processGO:1904100 positive regulation of protein O-linked glycosylation IEA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 molecular_functionGO:0000030 mannosyltransferase activity IEA
 molecular_functionGO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pzptm1Lex/Pzptm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001805 decreased IgG "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pzptm1Lex/Pzptm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0003954 abnormal Reichert s membrane "aberrant structure of the extraembryonic basement membrane that forms on the inner surface of the trophectoderm beginning at E6.0 and is secreted by the distal endoderm; required for the maternofetal exchange of nutrients and is important for the postgastrulation development" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005590 increased vasodilation "greater than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pzptm1Lex/Pzptm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pzptm1Lex/Pzptm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034126 Pomt2 / Q8BGQ4 / Protein O-mannosyl-transferase 2 / Q9UKY4* / protein O-mannosyltransferase 2*  / complex
 ENSMUSG00000039952 Dag1 / Q62165 / Dystroglycan Alpha-dystroglycan Beta-dystroglycan / Q14118* / dystroglycan 1*  / reaction






 

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