ENSMUSG00000039637


Mus musculus

Features
Gene ID: ENSMUSG00000039637
  
Biological name :Coro7
  
Synonyms : Coro7 / Coronin-7 / Q9D2V7
  
Possible biological names infered from orthology : CORO7-PAM16 / CORO7-PAM16 readthrough / P57737
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A1
Gene start: 4626133
Gene end: 4679777
  
Corresponding Affymetrix probe sets: 10437399 (MoGene1.0st)   1428147_at (Mouse Genome 430 2.0 Array)   1428148_s_at (Mouse Genome 430 2.0 Array)   1428149_at (Mouse Genome 430 2.0 Array)   1428150_at (Mouse Genome 430 2.0 Array)   1437146_x_at (Mouse Genome 430 2.0 Array)   1437524_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087966
Ensembl peptide - ENSMUSP00000118310
Ensembl peptide - ENSMUSP00000048489
NCBI entrez gene - 78885     See in Manteia.
MGI - MGI:1926135
RefSeq - NM_030205
RefSeq Peptide - NP_084481
swissprot - Q9D2V7
swissprot - E9PYU1
swissprot - G3X9L5
Ensembl - ENSMUSG00000039637
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 coro7ENSDARG00000089616Danio rerio
 CORO7ENSGALG00000038325Gallus gallus
 CORO7ENSG00000262246Homo sapiens
 CORO7-PAM16ENSG00000103426Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Coro1b / Q9WUM3 / Coronin-1B / Q9BR76*ENSMUSG0000002483517
Coro1a / O89053 / Coronin-1A / P31146*ENSMUSG0000003070717
Coro6 / Q920M5 / Coronin-6 / Q6QEF8*ENSMUSG0000002083616
Coro1c / Q9WUM4 / Coronin-1C / Q9ULV4*ENSMUSG0000000453016
Coro2a / Q8C0P5 / Coronin-2A / Q92828*ENSMUSG0000002833716
Coro2b / Q8BH44 / Coronin-2B / Q9UQ03*ENSMUSG0000004172915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015048  Domain of unknown function DUF1899
 IPR015505  Coronin
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027331  Coronin 7
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006895 Golgi to endosome transport ISS
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0030010 establishment of cell polarity IMP
 biological_processGO:0030041 actin filament polymerization ISS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002724 enhanced wound healing "increased ability to self-repair and close wounds" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:42016]
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Allelic Composition: Gnptabtm1Dkji/Gnptabtm1Dkji
Genetic Background: involves: 129 * C57BL/6

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gnptabtm1Dkji/Gnptabtm1Dkji
Genetic Background: involves: 129 * C57BL/6

 MP:0011709 increased fibroblast cell migration "greater frequency of or more rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Gnptabtm1Dkji/Gnptabtm1Dkji
Genetic Background: involves: 129 * C57BL/6

 MP:0011743 abnormal Golgi apparatus morphology "any structural anomaly of the compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack; Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations" [GO:0005794, MGI:mberry]
Show

Allelic Composition: Gnptabtm1Dkji/Gnptabtm1Dkji
Genetic Background: involves: 129 * C57BL/6

 MP:0020378 abnormal cell cytoskeleton morphology "any anomaly in the structure of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm" [GO:0005856, MGI:mberry]
Show

Allelic Composition: Gnptabtm1Dkji/Gnptabtm1Dkji
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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