ENSMUSG00000039782


Mus musculus

Features
Gene ID: ENSMUSG00000039782
  
Biological name :Cpeb2
  
Synonyms : Cpeb2 / cytoplasmic polyadenylation element-binding protein 2 isoform 1
  
Possible biological names infered from orthology : cytoplasmic polyadenylation element binding protein 2 / Q7Z5Q1
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B3
Gene start: 43233170
Gene end: 43289724
  
Corresponding Affymetrix probe sets: 10521602 (MoGene1.0st)   1434272_at (Mouse Genome 430 2.0 Array)   1443017_at (Mouse Genome 430 2.0 Array)   1447449_at (Mouse Genome 430 2.0 Array)   1458518_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109700
Ensembl peptide - ENSMUSP00000130921
Ensembl peptide - ENSMUSP00000125857
Ensembl peptide - ENSMUSP00000109699
NCBI entrez gene - 231207     See in Manteia.
MGI - MGI:2442640
RefSeq - XM_006503932
RefSeq - NM_175937
RefSeq - XM_006503927
RefSeq - XM_006503928
RefSeq - XM_006503929
RefSeq - XM_006503930
RefSeq - XM_006503931
RefSeq - NM_001177379
RefSeq Peptide - NP_787951
RefSeq Peptide - NP_001170850
swissprot - E9Q969
swissprot - E9Q5X2
swissprot - D3YUJ4
swissprot - A0A0H2UH22
Ensembl - ENSMUSG00000039782
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpeb2ENSDARG00000052604Danio rerio
 CPEB2ENSGALG00000014516Gallus gallus
 CPEB2ENSG00000137449Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cpeb3 / Q7TN99 / Cytoplasmic polyadenylation element-binding protein 3 / Q8NE35*ENSMUSG0000003965245
Cpeb4 / Q7TN98 / Cytoplasmic polyadenylation element-binding protein 4 / Q17RY0*ENSMUSG0000002030042
Cpeb1 / P70166 / Mus musculus cytoplasmic polyadenylation element binding protein 1 (Cpeb1), transcript variant 4, mRNA. / RPS17* / P08708* / Q9BZB8* / AC245033.1* / ribosomal protein S17* ...ENSMUSG0000002558616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR032296  Cytoplasmic polyadenylation element-binding protein, ZZ domain
 IPR034819  Cytoplasmic polyadenylation element-binding protein
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:2000766 negative regulation of cytoplasmic translation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0045182 translation regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001037 abnormal parasympathethetic neuron morphology "malformed or absent neurons of the autonomic nervous system that are responsible for innervation of smooth muscle, cardiac muscle and glands" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

 MP:0001945 bronchoconstriction "reduction in the caliber of the bronchus or bronchi" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

 MP:0001951 abnormal breathing "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0001952 increased airway responsiveness "more easily provoked into bronchoconstriction in bronchial provocation tests" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

 MP:0001957 apnea "absence of breathing; sometimes episodic" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17384]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0002204 abnormal neurotransmitter physiology "aberrant function or production of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0002337 abnormal whole-body plethysmography "anomaly in the measurements gathered in a chamber that encloses the body and in which changes in volume are recorded" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

 MP:0005574 decreased breathing frequency "fewer than the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

 MP:0006277 abnormal parasympathetic nervous system physiology "anomaly in the function of the craniosacral portion of the autonomic nervous system" [Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:78031]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

 MP:0012593 increased brain choline acetyltransferase activity "greater ability of the brain to catalyze the reaction: acetyl-CoA + choline = acetylcholine + CoA" [GO:0004102, http://orcid.org/0000-0001-5208-3432]
Show

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL/J

Allelic Composition: Chattm2(cre)Lowl/Chat+,Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu
Genetic Background: involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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