ENSG00000137449


Homo sapiens

Features
Gene ID: ENSG00000137449
  
Biological name :CPEB2
  
Synonyms : CPEB2 / cytoplasmic polyadenylation element binding protein 2 / Q7Z5Q1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p15.32
Gene start: 15002674
Gene end: 15070153
  
Corresponding Affymetrix probe sets: 226939_at (Human Genome U133 Plus 2.0 Array)   235462_at (Human Genome U133 Plus 2.0 Array)   235479_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443985
Ensembl peptide - ENSP00000423890
Ensembl peptide - ENSP00000424084
Ensembl peptide - ENSP00000259997
Ensembl peptide - ENSP00000334058
Ensembl peptide - ENSP00000371832
Ensembl peptide - ENSP00000371838
Ensembl peptide - ENSP00000414270
NCBI entrez gene - 132864     See in Manteia.
OMIM - 610605
RefSeq - XM_017007734
RefSeq - NM_001177381
RefSeq - NM_001177382
RefSeq - NM_001177383
RefSeq - NM_001177384
RefSeq - NM_182485
RefSeq - NM_182646
RefSeq - XM_005248135
RefSeq - XM_011513777
RefSeq - XM_017007733
RefSeq Peptide - NP_001170853
RefSeq Peptide - NP_001170854
RefSeq Peptide - NP_001170855
RefSeq Peptide - NP_872291
RefSeq Peptide - NP_872587
RefSeq Peptide - NP_001170852
swissprot - H0Y9D9
swissprot - J3KN18
swissprot - Q7Z5Q1
Ensembl - ENSG00000137449
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpeb2ENSDARG00000052604Danio rerio
 CPEB2ENSGALG00000014516Gallus gallus
 Cpeb2ENSMUSG00000039782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPEB4 / Q17RY0 / cytoplasmic polyadenylation element binding protein 4ENSG0000011374241
CPEB3 / Q8NE35 / cytoplasmic polyadenylation element binding protein 3ENSG0000010786441
AC245033.1ENSG0000026083615
CPEB1 / Q9BZB8 / cytoplasmic polyadenylation element binding protein 1ENSG0000021457515
RPS17 / P08708 / ribosomal protein S17ENSG000001827741


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR032296  Cytoplasmic polyadenylation element-binding protein, ZZ domain
 IPR034819  Cytoplasmic polyadenylation element-binding protein
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0034260 negative regulation of GTPase activity ISS
 biological_processGO:0034599 cellular response to oxidative stress ISS
 biological_processGO:0071243 cellular response to arsenic-containing substance ISS
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:1900248 negative regulation of cytoplasmic translational elongation ISS
 biological_processGO:2000766 negative regulation of cytoplasmic translation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:1990124 messenger ribonucleoprotein complex ISS
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IBA
 molecular_functionGO:0005095 GTPase inhibitor activity ISS
 molecular_functionGO:0008135 translation factor activity, RNA binding IBA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding ISS
 molecular_functionGO:0043022 ribosome binding IBA
 molecular_functionGO:0043023 ribosomal large subunit binding ISS
 molecular_functionGO:0043024 ribosomal small subunit binding ISS
 molecular_functionGO:0045182 translation regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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