ENSG00000107864


Homo sapiens

Features
Gene ID: ENSG00000107864
  
Biological name :CPEB3
  
Synonyms : CPEB3 / cytoplasmic polyadenylation element binding protein 3 / Q8NE35
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q23.32
Gene start: 92046692
Gene end: 92291087
  
Corresponding Affymetrix probe sets: 1555250_a_at (Human Genome U133 Plus 2.0 Array)   205773_at (Human Genome U133 Plus 2.0 Array)   239765_at (Human Genome U133 Plus 2.0 Array)   243651_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265997
Ensembl peptide - ENSP00000398310
Ensembl peptide - ENSP00000482128
NCBI entrez gene - 22849     See in Manteia.
OMIM - 610606
RefSeq - XM_011539520
RefSeq - NM_001178137
RefSeq - NM_014912
RefSeq - XM_011539515
RefSeq - XM_011539517
RefSeq - XM_011539518
RefSeq - XM_011539519
RefSeq - XM_005269630
RefSeq - XM_006717714
RefSeq - XM_006717715
RefSeq - XM_011539514
RefSeq Peptide - NP_055727
RefSeq Peptide - NP_001171608
swissprot - Q5QP71
swissprot - Q8NE35
Ensembl - ENSG00000107864
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpeb3ENSDARG00000060103Danio rerio
 CPEB3ENSGALG00000006912Gallus gallus
 Cpeb3ENSMUSG00000039652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPEB2 / Q7Z5Q1 / cytoplasmic polyadenylation element binding protein 2ENSG0000013744961
CPEB4 / Q17RY0 / cytoplasmic polyadenylation element binding protein 4ENSG0000011374259
AC245033.1ENSG0000026083623
CPEB1 / Q9BZB8 / cytoplasmic polyadenylation element binding protein 1ENSG0000021457523
RPS17 / P08708 / ribosomal protein S17ENSG000001827741


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR032296  Cytoplasmic polyadenylation element-binding protein, ZZ domain
 IPR034819  Cytoplasmic polyadenylation element-binding protein
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007616 long-term memory ISS
 biological_processGO:0017148 negative regulation of translation IDA
 biological_processGO:0045727 positive regulation of translation ISS
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IDA
 biological_processGO:0060998 regulation of dendritic spine development ISS
 biological_processGO:0060999 positive regulation of dendritic spine development ISS
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization IDA
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
 biological_processGO:1900248 negative regulation of cytoplasmic translational elongation ISS
 biological_processGO:1900365 positive regulation of mRNA polyadenylation ISS
 biological_processGO:2000766 negative regulation of cytoplasmic translation IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030014 CCR4-NOT complex IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0097440 apical dendrite ISS
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IBA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008135 translation factor activity, RNA binding ISS
 molecular_functionGO:0035613 RNA stem-loop binding ISS
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding ISS
 molecular_functionGO:0043022 ribosome binding IBA
 molecular_functionGO:0045182 translation regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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