ENSG00000214575


Homo sapiens

Features
Gene ID: ENSG00000214575
  
Biological name :CPEB1
  
Synonyms : CPEB1 / cytoplasmic polyadenylation element binding protein 1 / Q9BZB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q25.2
Gene start: 82543201
Gene end: 82648861
  
Corresponding Affymetrix probe sets: 219578_s_at (Human Genome U133 Plus 2.0 Array)   222903_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479625
Ensembl peptide - ENSP00000481009
Ensembl peptide - ENSP00000484549
Ensembl peptide - ENSP00000483951
Ensembl peptide - ENSP00000483857
Ensembl peptide - ENSP00000483590
Ensembl peptide - ENSP00000481010
Ensembl peptide - ENSP00000455044
Ensembl peptide - ENSP00000455268
Ensembl peptide - ENSP00000457137
Ensembl peptide - ENSP00000477557
Ensembl peptide - ENSP00000477715
Ensembl peptide - ENSP00000478598
Ensembl peptide - ENSP00000478841
NCBI entrez gene - 64506     See in Manteia.
OMIM - 607342
RefSeq - NM_001288820
RefSeq - NM_030594
RefSeq - NM_001079533
RefSeq - NM_001079534
RefSeq - NM_001079535
RefSeq - NM_001288819
RefSeq Peptide - NP_001275749
RefSeq Peptide - NP_085097
RefSeq Peptide - NP_001073001
RefSeq Peptide - NP_001073002
RefSeq Peptide - NP_001073003
RefSeq Peptide - NP_001275748
swissprot - Q9BZB8
swissprot - A0A087WXG7
swissprot - A0A087WVR7
swissprot - A0A087WUQ9
swissprot - A0A024R214
swissprot - H3BNX1
swissprot - H3BPD6
swissprot - H3BTE4
swissprot - A0A087X171
Ensembl - ENSG00000214575
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpeb1aENSDARG00000045932Danio rerio
 cpeb1bENSDARG00000008454Danio rerio
 CPEB1ENSGALG00000002150Gallus gallus
 Cpeb1ENSMUSG00000025586Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC245033.1ENSG0000026083681
CPEB4 / Q17RY0 / cytoplasmic polyadenylation element binding protein 4ENSG0000011374231
CPEB3 / Q8NE35 / cytoplasmic polyadenylation element binding protein 3ENSG0000010786429
CPEB2 / Q7Z5Q1 / cytoplasmic polyadenylation element binding protein 2ENSG0000013744928
RPS17 / P08708 / ribosomal protein S17ENSG000001827742


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR032292  Cytoplasmic polyadenylation element-binding protein 1, N-terminal
 IPR032296  Cytoplasmic polyadenylation element-binding protein, ZZ domain
 IPR034819  Cytoplasmic polyadenylation element-binding protein
 IPR034977  CPEB-1, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:2000766 negative regulation of cytoplasmic translation IMP
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IBA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding IBA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding ISS
 molecular_functionGO:0043022 ribosome binding IBA
 molecular_functionGO:0045182 translation regulator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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