ENSDARG00000008454


Danio rerio

Features
Gene ID: ENSDARG00000008454
  
Biological name :cpeb1b
  
Synonyms : cpeb1b / cytoplasmic polyadenylation element binding protein 1b / Q9YGX5
  
Possible biological names infered from orthology : AC245033.1 / CPEB1 / cytoplasmic polyadenylation element binding protein 1 / Mus musculus cytoplasmic polyadenylation element binding protein 1 (Cpeb1), transcript variant 4, mRNA. / P08708 / P70166 / Q9BZB8 / ribosomal protein S17 / RPS17
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 48240707
Gene end: 48251235
  
Corresponding Affymetrix probe sets: Dr.614.1.S2_at (Zebrafish Array)   NM_131427_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000028099
Ensembl peptide - ENSDARP00000089674
NCBI entrez gene - 30702     See in Manteia.
RefSeq - NM_131427
RefSeq - XM_021477394
RefSeq Peptide - NP_571502
swissprot - A2CE67
swissprot - Q9YGX5
swissprot - A2CE68
ZFIN ID - ZDB-GENE-990927-1
Ensembl - ENSDARG00000008454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CPEB1ENSGALG00000002150Gallus gallus
 AC245033.1ENSG00000260836Homo sapiens
 CPEB1ENSG00000214575Homo sapiens
 RPS17ENSG00000182774Homo sapiens
 Cpeb1ENSMUSG00000025586Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cpeb1a / cytoplasmic polyadenylation element binding protein 1a / CPEB1* / RPS17* / P08708* / Q9BZB8* / P70166* / AC245033.1* / ribosomal protein S17* / cytoplasmic polyadenylation element ...ENSDARG0000004593249
cpeb4b / cytoplasmic polyadenylation element binding protein 4b / CPEB4* / Q17RY0* / cytoplasmic polyadenylation element binding protein 4*ENSDARG0000010049928
cpeb4a / cytoplasmic polyadenylation element binding protein 4a / CPEB4* / Q17RY0* / Q7TN98* / cytoplasmic polyadenylation element binding protein 4*ENSDARG0000005669126
cpeb3 / cytoplasmic polyadenylation element binding protein 3 / Q7TN99* / Q8NE35*ENSDARG0000006010325
cpeb2 / cytoplasmic polyadenylation element binding protein 2 / Q7Z5Q1*ENSDARG0000005260423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR032292  Cytoplasmic polyadenylation element-binding protein 1, N-terminal
 IPR032296  Cytoplasmic polyadenylation element-binding protein, ZZ domain
 IPR034819  Cytoplasmic polyadenylation element-binding protein
 IPR034977  CPEB-1, RNA recognition motif 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0032869 cellular response to insulin stimulus ISS
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 biological_processGO:0071456 cellular response to hypoxia ISS
 biological_processGO:2000766 negative regulation of cytoplasmic translation ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IBA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IPI
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008135 translation factor activity, RNA binding IBA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding ISS
 molecular_functionGO:0043022 ribosome binding IBA
 molecular_functionGO:0045182 translation regulator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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