ENSMUSG00000040385


Mus musculus

Features
Gene ID: ENSMUSG00000040385
  
Biological name :Ppp1ca
  
Synonyms : P62137 / Ppp1ca / protein phosphatase 1, catalytic subunit, alpha isoform
  
Possible biological names infered from orthology : P62136 / protein phosphatase 1 catalytic subunit alpha
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 4192158
Gene end: 4195419
  
Corresponding Affymetrix probe sets: 10460376 (MoGene1.0st)   1460165_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039109
NCBI entrez gene - 19045     See in Manteia.
MGI - MGI:103016
RefSeq - NM_031868
RefSeq Peptide - NP_114074
swissprot - P62137
Ensembl - ENSMUSG00000040385
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1caaENSDARG00000003486Danio rerio
 P62136ENSG00000172531Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P63087 / Ppp1cc / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit / P36873* / protein phosphatase 1 catalytic subunit gamma*ENSMUSG0000000445590
P62141 / Ppp1cb / Serine/threonine-protein phosphatase PP1-beta catalytic subunit / P62140* / protein phosphatase 1 catalytic subunit beta*ENSMUSG0000001495686


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like
 IPR031675  Serine-threonine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0005979 regulation of glycogen biosynthetic process IEA
 biological_processGO:0005981 regulation of glycogen catabolic process IEA
 biological_processGO:0006417 regulation of translation TAS
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0009987 cellular process TAS
 biological_processGO:0010288 response to lead ion IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0032922 circadian regulation of gene expression IDA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IMP
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 cellular_componentGO:0000164 protein phosphatase type 1 complex IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0042587 glycogen granule IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0072357 PTW/PP1 phosphatase complex ISO
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IDA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008157 protein phosphatase 1 binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IEA


Pathways (from Reactome)
Pathway description
DARPP-32 events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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