ENSMUSG00000040478


Mus musculus

Features
Gene ID: ENSMUSG00000040478
  
Biological name :Prdm13
  
Synonyms : E9PZZ1 / Prdm13 / PR domain zinc finger protein 13
  
Possible biological names infered from orthology : PR/SET domain 13 / Q9H4Q3
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A3
Gene start: 21677480
Gene end: 21685963
  
Corresponding Affymetrix probe sets: 10511795 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000092761
Ensembl peptide - ENSMUSP00000075562
NCBI entrez gene - 230025     See in Manteia.
MGI - MGI:2448528
RefSeq - NM_001080771
RefSeq - XM_006537806
RefSeq - XM_006537807
RefSeq Peptide - NP_001074240
swissprot - E9PZZ1
Ensembl - ENSMUSG00000040478
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdm13ENSDARG00000078701Danio rerio
 PRDM13ENSGALG00000038476Gallus gallus
 PRDM13ENSG00000112238Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2A935 / Prdm16 / PR domain zinc finger protein 16 / Q9HAZ2* / PR/SET domain 16*ENSMUSG0000003941014
Mecom / P14404 / MDS1 and EVI1 complex locus / Q03112*ENSMUSG0000002768412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016571 histone methylation IEA
 biological_processGO:0022008 neurogenesis IDA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042054 histone methyltransferase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003734 abnormal inner plexiform layer morphology "malformation/anomalous structure of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

Allelic Composition: Prdm13tm1.1Tfur/Prdm13tm1.1Tfur,Tg(Dkk3-cre)D9Tfur/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N

 MP:0008106 decreased amacrine cell number "reduction in the number of one of the three types of interneurons found in the inner nuclear layer of the mature retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

Allelic Composition: Prdm13tm1.1Tfur/Prdm13tm1.1Tfur,Tg(Dkk3-cre)D9Tfur/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N

 MP:0008511 thin retinal inner nuclear layer "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

 MP:0008513 thin retinal inner plexiform layer "reduced thickness of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

 MP:0009619 abnormal optokinetic reflex "any anomaly in the nystagmus or deviation of the eyes in response to stimulation of the visual system by movement; normally, this reflex functions to stabilize a moving image on the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

Allelic Composition: Prdm13tm1.1Tfur/Prdm13tm1.1Tfur,Tg(Dkk3-cre)D9Tfur/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N

 MP:0011831 abnormal visual contrast sensitivity "any abnormality in the ability to distinguish between increments of light versus dark" [MGI:smb]
Show

Allelic Composition: Leprm1Clo/Leprm1Clo
Genetic Background: STOCK Leprm1Clo/GrsrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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