ENSMUSG00000041044


Mus musculus

Features
Gene ID: ENSMUSG00000041044
  
Biological name :Lrit1
  
Synonyms : Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 / Lrit1 / Q8K099
  
Possible biological names infered from orthology : leucine rich repeat, Ig-like and transmembrane domains 1 / Q9P2V4
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 37054830
Gene end: 37064946
  
Corresponding Affymetrix probe sets: 10414163 (MoGene1.0st)   1441110_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113964
NCBI entrez gene - 239037     See in Manteia.
MGI - MGI:2385320
RefSeq - NM_146245
RefSeq - XM_017316012
RefSeq Peptide - NP_666357
swissprot - Q8K099
Ensembl - ENSMUSG00000041044
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrit1aENSDARG00000019179Danio rerio
 lrit1bENSDARG00000099406Danio rerio
 LRIT1ENSGALG00000002303Gallus gallus
 LRIT1ENSG00000148602Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lrit3 / W8DXL4 / Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 / Q3SXY7* / leucine rich repeat, Ig-like and transmembrane domains 3*ENSMUSG0000009386534
Lrit2 / Q6PFC5 / Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 / A6NDA9* / leucine rich repeat, Ig-like and transmembrane domains 2*ENSMUSG0000004341824
Islr2 / Q5RKR3 / Immunoglobulin superfamily containing leucine-rich repeat protein 2 / Q6UXK2* / immunoglobulin superfamily containing leucine rich repeat 2*ENSMUSG0000005124321
Islr / Q6GU68 / Immunoglobulin superfamily containing leucine-rich repeat protein / O14498* / immunoglobulin superfamily containing leucine rich repeat*ENSMUSG0000003720615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

 MP:0009619 abnormal optokinetic reflex "any anomaly in the nystagmus or deviation of the eyes in response to stimulation of the visual system by movement; normally, this reflex functions to stabilize a moving image on the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Adora2btm1Msit/Adora2btm1Msit,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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