ENSMUSG00000042350


Mus musculus

Features
Gene ID: ENSMUSG00000042350
  
Biological name :Arel1
  
Synonyms : Apoptosis-resistant E3 ubiquitin protein ligase 1 / Arel1 / Q8CHG5
  
Possible biological names infered from orthology : O15033
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: D1
Gene start: 84918148
Gene end: 84970900
  
Corresponding Affymetrix probe sets: 10401564 (MoGene1.0st)   1433767_at (Mouse Genome 430 2.0 Array)   1454721_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048780
Ensembl peptide - ENSMUSP00000130259
Ensembl peptide - ENSMUSP00000129213
Ensembl peptide - ENSMUSP00000129147
Ensembl peptide - ENSMUSP00000127426
Ensembl peptide - ENSMUSP00000126523
Ensembl peptide - ENSMUSP00000126508
NCBI entrez gene - 68497     See in Manteia.
MGI - MGI:1915747
RefSeq - XM_006516191
RefSeq - NM_178065
RefSeq - XM_006516189
RefSeq - XM_006516190
RefSeq Peptide - NP_835166
swissprot - E9Q2W2
swissprot - E9Q7I2
swissprot - Q8CHG5
swissprot - E9PZX5
swissprot - E9PYE5
swissprot - E9PY98
swissprot - E9PYA6
Ensembl - ENSMUSG00000042350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AREL1ENSDARG00000100359Danio rerio
 AREL1ENSGALG00000010270Gallus gallus
 AREL1ENSG00000119682Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Huwe1 / Q7TMY8 / E3 ubiquitin-protein ligase HUWE1 / Q7Z6Z7* / HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase*ENSMUSG0000002526130
Ubr5 / ubiquitin protein ligase E3 component n-recognin 5 / O95071*ENSMUSG0000003748720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR017868  Filamin/ABP280 repeat-like
 IPR035983  HECT, E3 ligase catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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