ENSMUSG00000042390


Mus musculus

Features
Gene ID: ENSMUSG00000042390
  
Biological name :Gatad2b
  
Synonyms : Gatad2b / Q8VHR5 / Transcriptional repressor p66-beta
  
Possible biological names infered from orthology : GATA zinc finger domain containing 2B / Q8WXI9
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 90293178
Gene end: 90363407
  
Corresponding Affymetrix probe sets: 10493758 (MoGene1.0st)   1425075_at (Mouse Genome 430 2.0 Array)   1432979_at (Mouse Genome 430 2.0 Array)   1437474_at (Mouse Genome 430 2.0 Array)   1437507_at (Mouse Genome 430 2.0 Array)   1447026_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142617
Ensembl peptide - ENSMUSP00000145623
Ensembl peptide - ENSMUSP00000143085
Ensembl peptide - ENSMUSP00000041370
Ensembl peptide - ENSMUSP00000142514
NCBI entrez gene - 229542     See in Manteia.
MGI - MGI:2443225
RefSeq - XM_006501359
RefSeq - XM_006501361
RefSeq - NM_139304
RefSeq - XM_006501360
RefSeq Peptide - NP_647465
swissprot - Q8VHR5
swissprot - A1L3S7
swissprot - A0A0U1RNM2
Ensembl - ENSMUSG00000042390
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gatad2bENSDARG00000005834Danio rerio
 Q8WXI9ENSG00000143614Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CHY6 / Gatad2a / Transcriptional repressor p66 alpha / Q86YP4* / GATA zinc finger domain containing 2A*ENSMUSG0000003618042


Protein motifs (from Interpro)
Interpro ID Name
 IPR000679  Zinc finger, GATA-type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR032346  Transcriptional repressor p66, coiled-coil MBD2-interaction domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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