ENSMUSG00000042737


Mus musculus

Features
Gene ID: ENSMUSG00000042737
  
Biological name :Dpm3
  
Synonyms : Dolichol-phosphate mannosyltransferase subunit 3 / Dpm3 / Q9D1Q4
  
Possible biological names infered from orthology : dolichyl-phosphate mannosyltransferase subunit 3 / Q9P2X0
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 89259358
Gene end: 89267079
  
Corresponding Affymetrix probe sets: 10493490 (MoGene1.0st)   1452729_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040860
Ensembl peptide - ENSMUSP00000103086
NCBI entrez gene - 68563     See in Manteia.
MGI - MGI:1915813
RefSeq - XM_006501983
RefSeq - NM_026767
RefSeq Peptide - NP_081043
swissprot - Q9D1Q4
Ensembl - ENSMUSG00000042737
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpm3ENSDARG00000058650Danio rerio
 DPM3ENSG00000179085Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013174  Dolichol-phosphate mannosyltransferase subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006506 GPI anchor biosynthetic process IBA
 biological_processGO:0031647 regulation of protein stability ISO
 biological_processGO:0035269 protein O-linked mannosylation IBA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane ISS
 cellular_componentGO:0033185 dolichol-phosphate-mannose synthase complex IBA
 molecular_functionGO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity IBA


Pathways (from Reactome)
Pathway description
Synthesis of dolichyl-phosphate mannose


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026810 Dpm2 / Q9Z324 / Dolichol phosphate-mannose biosynthesis regulatory protein / O94777* / dolichyl-phosphate mannosyltransferase subunit 2, regulatory*  / complex
 ENSMUSG00000078919 Dpm1 / O70152 / Dolichol-phosphate mannosyltransferase subunit 1 / O60762* / dolichyl-phosphate mannosyltransferase subunit 1, catalytic*  / complex






 

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