ENSMUSG00000078919


Mus musculus

Features
Gene ID: ENSMUSG00000078919
  
Biological name :Dpm1
  
Synonyms : Dolichol-phosphate mannosyltransferase subunit 1 / Dpm1 / O70152
  
Possible biological names infered from orthology : dolichyl-phosphate mannosyltransferase subunit 1, catalytic / O60762
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 168209048
Gene end: 168230591
  
Corresponding Affymetrix probe sets: 10489946 (MoGene1.0st)   1419353_at (Mouse Genome 430 2.0 Array)   1420253_at (Mouse Genome 430 2.0 Array)   1449438_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118776
Ensembl peptide - ENSMUSP00000096671
Ensembl peptide - ENSMUSP00000104816
NCBI entrez gene - 13480     See in Manteia.
MGI - MGI:1330239
RefSeq - NM_010072
RefSeq - NM_001310084
RefSeq Peptide - NP_001297013
RefSeq Peptide - NP_034202
swissprot - O70152
swissprot - F8WII3
swissprot - A2BDX2
Ensembl - ENSMUSG00000078919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpm1ENSDARG00000057011Danio rerio
 DPM1ENSGALG00000017366Gallus gallus
 DPM1ENSG00000000419Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O70152 / Gm20716 / predicted gene 20716 / DPM1* / O60762* / dolichyl-phosphate mannosyltransferase subunit 1, catalytic*ENSMUSG00000093752100


Protein motifs (from Interpro)
Interpro ID Name
 IPR001173  Glycosyltransferase 2-like
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006506 GPI anchor biosynthetic process ISS
 biological_processGO:0019348 dolichol metabolic process ISO
 biological_processGO:0035268 protein mannosylation ISO
 biological_processGO:0035269 protein O-linked mannosylation ISO
 biological_processGO:0097502 mannosylation IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0033185 dolichol-phosphate-mannose synthase complex ISO
 molecular_functionGO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity ISO
 molecular_functionGO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000042737 Dpm3 / Q9D1Q4 / Dolichol-phosphate mannosyltransferase subunit 3 / Q9P2X0* / dolichyl-phosphate mannosyltransferase subunit 3*  / complex
 ENSMUSG00000026810 Dpm2 / Q9Z324 / Dolichol phosphate-mannose biosynthesis regulatory protein / O94777* / dolichyl-phosphate mannosyltransferase subunit 2, regulatory*  / complex






 

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