ENSMUSG00000043262


Mus musculus

Features
Gene ID: ENSMUSG00000043262
  
Biological name :Uevld
  
Synonyms : Q3U1V6 / UEV and lactate/malate dehyrogenase domains / Uevld
  
Possible biological names infered from orthology : Q8IX04
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 46923216
Gene end: 46958527
  
Corresponding Affymetrix probe sets: 10399036 (MoGene1.0st)   10563649 (MoGene1.0st)   1421785_at (Mouse Genome 430 2.0 Array)   1455551_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146385
Ensembl peptide - ENSMUSP00000147932
Ensembl peptide - ENSMUSP00000146930
Ensembl peptide - ENSMUSP00000091964
NCBI entrez gene - 54122     See in Manteia.
MGI - MGI:1860490
RefSeq - XM_006540993
RefSeq - XM_006540994
RefSeq - NM_001040695
RefSeq Peptide - NP_001035785
swissprot - Q3U1V6
swissprot - A0A1B0GSG9
swissprot - A0A140LHE8
Ensembl - ENSMUSG00000043262
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uevldENSDARG00000009266Danio rerio
 UEVLDENSGALG00000006342Gallus gallus
 UEVLDENSG00000151116Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ldha / P06151 / L-lactate dehydrogenase A chain / P00338* / lactate dehydrogenase A*ENSMUSG0000006322928
Ldhal6b / lactate dehydrogenase A like 6B / Q9BYZ2*ENSMUSG0000010195927
Ldhb / P16125 / L-lactate dehydrogenase B chain / P07195* / lactate dehydrogenase B*ENSMUSG0000003024627
Ldhc / P00342 / lactate dehydrogenase C / P07864*ENSMUSG0000003085125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001557  L-lactate/malate dehydrogenase
 IPR008883  Ubiquitin E2 variant, N-terminal
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR022383  Lactate/malate dehydrogenase, C-terminal
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0008211 decreased mature B cell number "reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0013655 decreased CD103-positive CD11b-low dendritic cell number "reduction in the number of CD11b-low dendritic cells expressing CD103, a marker of tissue residency" [MGI:Saran, PMID:23516985]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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