ENSMUSG00000044005


Mus musculus

Features
Gene ID: ENSMUSG00000044005
  
Biological name :Gls2
  
Synonyms : Gls2 / Glutaminase liver isoform, mitochondrial / Q571F8
  
Possible biological names infered from orthology : glutaminase 2 / Q9UI32
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 128194457
Gene end: 128210004
  
Corresponding Affymetrix probe sets: 10367154 (MoGene1.0st)   1435245_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123436
Ensembl peptide - ENSMUSP00000124797
Ensembl peptide - ENSMUSP00000119763
Ensembl peptide - ENSMUSP00000124239
Ensembl peptide - ENSMUSP00000115788
Ensembl peptide - ENSMUSP00000047376
NCBI entrez gene - 216456     See in Manteia.
MGI - MGI:2143539
RefSeq - NM_001033264
RefSeq - NM_001285779
RefSeq - NM_001285777
RefSeq Peptide - NP_001272706
RefSeq Peptide - NP_001028436
RefSeq Peptide - NP_001272708
swissprot - Q571F8
swissprot - D6RI88
swissprot - E0CXA4
swissprot - E0CYF7
swissprot - F6SJZ7
swissprot - F6WPK7
Ensembl - ENSMUSG00000044005
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gls2aENSDARG00000069095Danio rerio
 gls2bENSDARG00000002917Danio rerio
 GLS2ENSG00000135423Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gls / D3Z7P3 / Glutaminase kidney isoform, mitochondrial / O94925* / glutaminase*ENSMUSG0000002610366


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR012338  Beta-lactamase/transpeptidase-like
 IPR015868  Glutaminase
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006537 glutamate biosynthetic process IBA
 biological_processGO:0006541 glutamine metabolic process IEA
 biological_processGO:0006543 glutamine catabolic process IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0004359 glutaminase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
TP53 Regulates Metabolic Genes
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000044005 Gls2 / Q571F8 / Glutaminase liver isoform, mitochondrial / Q9UI32* / glutaminase 2*  / complex






 

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