ENSMUSG00000044308


Mus musculus

Features
Gene ID: ENSMUSG00000044308
  
Biological name :Ubr3
  
Synonyms : Q5U430 / ubiquitin protein ligase E3 component n-recognin 3 / Ubr3
  
Possible biological names infered from orthology : Q6ZT12 / ubiquitin protein ligase E3 component n-recognin 3 (putative)
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C2
Gene start: 69897246
Gene end: 70024013
  
Corresponding Affymetrix probe sets: 10472621 (MoGene1.0st)   10472630 (MoGene1.0st)   1429107_at (Mouse Genome 430 2.0 Array)   1444469_at (Mouse Genome 430 2.0 Array)   1453029_s_at (Mouse Genome 430 2.0 Array)   1458654_at (Mouse Genome 430 2.0 Array)   1460455_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060159
Ensembl peptide - ENSMUSP00000107870
Ensembl peptide - ENSMUSP00000121401
Ensembl peptide - ENSMUSP00000122027
NCBI entrez gene - 68795     See in Manteia.
MGI - MGI:1861100
RefSeq - XM_011239758
RefSeq - NM_001303033
RefSeq - NM_177783
RefSeq - XM_006500116
RefSeq - XM_006500117
RefSeq - XM_006500119
RefSeq Peptide - NP_808451
RefSeq Peptide - NP_001289962
swissprot - F6RDS0
swissprot - F6QC57
swissprot - Q5U430
swissprot - A2AV05
Ensembl - ENSMUSG00000044308
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubr3ENSDARG00000042508Danio rerio
 ENSGALG00000009608Gallus gallus
 ENSGALG00000035605Gallus gallus
 UBR3ENSG00000144357Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ubr1 / O70481 / ubiquitin protein ligase E3 component n-recognin 1 / Q8IWV7*ENSMUSG0000002727217
Ubr2 / Q6WKZ8 / ubiquitin protein ligase E3 component n-recognin 2 / Q8IWV8*ENSMUSG0000002397717


Protein motifs (from Interpro)
Interpro ID Name
 IPR003126  Zinc finger, UBR-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001967 suckling behavior IMP
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0009792 embryo development ending in birth or egg hatching IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0042048 olfactory behavior IMP
 biological_processGO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

 MP:0003964 abnormal noradrenaline level "aberrant concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

 MP:0004512 anosmia "loss of the sense of smell" [mberry:Melissa Berry_Genetic Resources Curator]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr