ENSMUSG00000046139


Mus musculus

Features
Gene ID: ENSMUSG00000046139
  
Biological name :Patl1
  
Synonyms : 1 / Patl1 / Q3TC46
  
Possible biological names infered from orthology : PAT1 homolog 1, processing body mRNA decay factor / Q86TB9
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 11912399
Gene end: 11945096
  
Corresponding Affymetrix probe sets: 10461671 (MoGene1.0st)   1433697_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060398
NCBI entrez gene - 225929     See in Manteia.
MGI - MGI:2147679
RefSeq - NM_172635
RefSeq - XM_006526947
RefSeq Peptide - NP_766223
swissprot - Q3TC46
Ensembl - ENSMUSG00000046139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 patl1ENSDARG00000017423Danio rerio
 PATL1ENSG00000166889Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
2 / Patl2 / A2ARM1 / C9JE40* / PAT1 homolog 2*ENSMUSG0000002723321


Protein motifs (from Interpro)
Interpro ID Name
 IPR019167  Topoisomerase II-associated protein PAT1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
 biological_processGO:0017148 negative regulation of translation ISO
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IEA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 molecular_functionGO:0002151 G-quadruplex RNA binding ISO
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0008266 poly(U) RNA binding IEA
 molecular_functionGO:0030371 translation repressor activity ISO
 molecular_functionGO:0034046 poly(G) binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Otub1tm1b(EUCOMM)Hmgu/Otub1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Otub1tm1b(EUCOMM)Hmgu/H

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Otub1tm1b(EUCOMM)Hmgu/Otub1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Otub1tm1b(EUCOMM)Hmgu/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Otub1tm1b(EUCOMM)Hmgu/Otub1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Otub1tm1b(EUCOMM)Hmgu/H

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Otub1tm1b(EUCOMM)Hmgu/Otub1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Otub1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr