ENSMUSG00000046480


Mus musculus

Features
Gene ID: ENSMUSG00000046480
  
Biological name :Scn4b
  
Synonyms : Q7M729 / Scn4b / Sodium channel subunit beta-4
  
Possible biological names infered from orthology : Q8IWT1 / sodium voltage-gated channel beta subunit 4
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.2
Gene start: 45138395
Gene end: 45154152
  
Corresponding Affymetrix probe sets: 10584862 (MoGene1.0st)   1434008_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062507
NCBI entrez gene - 399548     See in Manteia.
MGI - MGI:2687406
RefSeq - NM_001013390
RefSeq Peptide - NP_001013408
swissprot - Q1MXF9
swissprot - Q7M729
Ensembl - ENSMUSG00000046480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn4baENSDARG00000099031Danio rerio
 scn4bbENSDARG00000060319Danio rerio
 SCN4BENSGALG00000007409Gallus gallus
 SCN4BENSG00000177098Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Scn2b / Q56A07 / Sodium channel subunit beta-2 / O60939* / sodium voltage-gated channel beta subunit 2*ENSMUSG0000007030425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000920  Myelin P0 protein-related
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport ISO
 biological_processGO:0010765 positive regulation of sodium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:0086002 cardiac muscle cell action potential involved in contraction IEA
 biological_processGO:0086012 membrane depolarization during cardiac muscle cell action potential IEA
 biological_processGO:0086016 AV node cell action potential ISO
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:2000649 regulation of sodium ion transmembrane transporter activity ISS
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014704 intercalated disc IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA
 molecular_functionGO:0017080 sodium channel regulator activity IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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