ENSMUSG00000048787


Mus musculus

Features
Gene ID: ENSMUSG00000048787
  
Biological name :Dcun1d3
  
Synonyms : DCN1-like protein 3 / Dcun1d3 / Q8K0V2
  
Possible biological names infered from orthology : defective in cullin neddylation 1 domain containing 3 / Q8IWE4
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F2
Gene start: 119852796
Gene end: 119896298
  
Corresponding Affymetrix probe sets: 10567423 (MoGene1.0st)   1436673_at (Mouse Genome 430 2.0 Array)   1437763_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118439
Ensembl peptide - ENSMUSP00000115386
Ensembl peptide - ENSMUSP00000147253
Ensembl peptide - ENSMUSP00000058968
Ensembl peptide - ENSMUSP00000095686
Ensembl peptide - ENSMUSP00000102129
NCBI entrez gene - 233805     See in Manteia.
MGI - MGI:2679003
RefSeq - XM_017322200
RefSeq - XM_006507681
RefSeq - XM_011241748
RefSeq - XM_011241749
RefSeq - XM_011241750
RefSeq - XM_011241751
RefSeq - NM_001163703
RefSeq - NM_173408
RefSeq Peptide - NP_001157175
RefSeq Peptide - NP_775584
swissprot - D3Z0Q3
swissprot - Q8K0V2
swissprot - D3YWG7
Ensembl - ENSMUSG00000048787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcun1d3ENSDARG00000011493Danio rerio
 DCUN1D3ENSGALG00000002267Gallus gallus
 Q8IWE4ENSG00000188215Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BZJ7 / Dcun1d2 / DCN1-like protein 2 / Q6PH85* / defective in cullin neddylation 1 domain containing 2*ENSMUSG0000003850634
Q9QZ73 / Dcun1d1 / DCN1-like protein 1 ENSMUSG0000002770833
Tes3-ps / testis derived transcript 3, pseudogeneENSMUSG0000011325532
Q8CCA0 / Dcun1d4 / DCN1-like protein 4 / Q92564* / defective in cullin neddylation 1 domain containing 4*ENSMUSG0000005167425
Q9CXV9 / Dcun1d5 / DCN1-like protein 5 / Q9BTE7* / defective in cullin neddylation 1 domain containing 5*ENSMUSG0000003200223


Protein motifs (from Interpro)
Interpro ID Name
 IPR005176  Potentiating neddylation domain
 IPR014764  Defective-in-cullin neddylation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009314 response to radiation IBA
 biological_processGO:0010225 response to UV-C ISS
 biological_processGO:0010332 response to gamma radiation ISS
 biological_processGO:0030308 negative regulation of cell growth ISS
 biological_processGO:0043065 positive regulation of apoptotic process ISS
 biological_processGO:0045116 protein neddylation IBA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IBA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle ISS
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0032182 ubiquitin-like protein binding IBA
 molecular_functionGO:0097602 cullin family protein binding IBA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / reaction / complex
 ENSMUSG00000031143 Ccdc22 / Q9JIG7 / Coiled-coil domain-containing protein 22 / O60826* / coiled-coil domain containing 22*  / complex / reaction
 ENSMUSG00000029686 Cul1 / Q9WTX6 / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA. / Q13616* / cullin 1*  / reaction / complex
 ENSMUSG00000036309 Skp1a / Q9WTX5 / S-phase kinase-associated protein 1A / SKP1* / P63208* / AC104109.3* / S-phase kinase associated protein 1*  / reaction / complex
 ENSMUSG00000051355 Commd1 / Q8K4M5 / COMM domain-containing protein 1 / Q8N668* / copper metabolism domain containing 1*  / reaction / complex






 

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