ENSMUSG00000049086


Mus musculus

Features
Gene ID: ENSMUSG00000049086
  
Biological name :Bmyc
  
Synonyms : Bmyc / Protein B-Myc / Q6P8Z1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 25706739
Gene end: 25707721
  
Corresponding Affymetrix probe sets: 10470182 (MoGene1.0st)   1428669_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097885
NCBI entrez gene - 107771     See in Manteia.
MGI - MGI:88184
RefSeq - NM_023326
RefSeq Peptide - NP_075815
swissprot - A0PJL6
swissprot - Q6P8Z1
Ensembl - ENSMUSG00000049086
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mycaENSDARG00000045695Danio rerio
 mycbENSDARG00000007241Danio rerio
 MYCENSGALG00000033631Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myc / P01108 / myelocytomatosis oncogene / P01106* / MYC proto-oncogene, bHLH transcription factor*ENSMUSG0000002234656
Mycn / P03966 / N-myc proto-onco protein / P04198* / MYCN proto-oncogene, bHLH transcription factor*ENSMUSG0000003716929
Mycs / Q9Z304 / Protein S-Myc ENSMUSG0000004459726
Mycl / P10166 / Protein L-Myc / P12524* / MYCL proto-oncogene, bHLH transcription factor*ENSMUSG0000002865424


Protein motifs (from Interpro)
Interpro ID Name
 IPR002418  Transcription regulator Myc
 IPR012682  Transcription regulator Myc, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005819 spindle IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0001751 increased circulating luteinizing hormone level "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0009248 small caput "decrease in the average size of the head of the epididymis" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0010831 partial lethality "the appearance of lower than Mendelian ratios of offspring of a given genotype due to death of some, but not all of the organisms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

 MP:0011385 abnormal testosterone level "anomaly in the concentration of a potent androgen that promotes development of male secondary sex characteristics and the development of spermatozoa and may regulate sexual desire and help maintain bone and muscle health in both males and females" [ISBN:0-683-40008-8]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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